Cystatins that occur primarily as intracellular proteins. Cystatins that occur as plasma proteins. Cystatins that occur primarily as extracellular proteins. A homologous group of endogenous CYSTEINE PROTEINASE INHIBITORS. The cystatins inhibit most CYSTEINE ENDOPEPTIDASES such as PAPAIN, and other peptidases which have a sulfhydryl group at the active site.
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