Link to this page
Medical Subject Headings
| Preferred Name | Up-Regulation | |
| Synonyms |
Upregulation Up-Regulation (Physiology) Receptor Up-Regulation Up Regulation |
|
| Definitions |
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins. A positive regulatory process that increases ligand-receptor interactions. Increase in receptor binding after ligand exposure can result from receptor activation, aggregation, increase in half-life, and/or an increase in gene expression that leads to de novo receptor synthesis. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D015854 |
|
| altLabel |
Upregulation Up-Regulation (Physiology) Receptor Up-Regulation Up Regulation
|
|
| AQL |
DE ES GE IM PH RE
|
|
| cui |
C0041904 C0949479
|
|
| DC |
1
|
|
| definition |
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins. A positive regulatory process that increases ligand-receptor interactions. Increase in receptor binding after ligand exposure can result from receptor activation, aggregation, increase in half-life, and/or an increase in gene expression that leads to de novo receptor synthesis.
|
|
| DX |
19900101
|
|
| FX |
D015536 D025461
|
|
| HN |
2002 (1990)
|
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000941 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 |
|
| Inverse of RO | ||
| Machine permutation |
2002; see Up-Regulation (Physiology) 1990-2001
|
|
| MDA |
19890526
|
|
| MMR |
20160617
|
|
| MN |
G07.690.773.998 G05.308.850 G02.111.905
|
|
| notation |
D015854
|
|
| prefLabel |
Up-Regulation
|
|
| TERMUI |
T047048 T430673 T047049 T047050
|
|
| TH |
NLM (2002) NLM (1990)
|
|
| tui |
T044
|
|
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D001669 |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |