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Last uploaded: August 28, 2024

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Preferred Name	Dideoxynucleosides
Synonyms	2',3'-Dideoxynucleosides ddNus 2',3' Dideoxynucleosides Dideoxyribonucleosides
Definitions	Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
ID	http://purl.bioontology.org/ontology/MESH/D015224
altLabel	2',3'-Dideoxynucleosides ddNus 2',3' Dideoxynucleosides Dideoxyribonucleosides
AN	antivirals & antimetabolites
AQL	AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0282384 C0012136 C0282385
DC	1
definition	Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
DX	19890101
HN	89
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	0
isa	http://purl.bioontology.org/ontology/MESH/D000963 http://purl.bioontology.org/ontology/MESH/D000998 http://purl.bioontology.org/ontology/MESH/D018894
Machine permutation	89
Mapped from	http://purl.bioontology.org/ontology/MESH/C083225 http://purl.bioontology.org/ontology/MESH/C050220 http://purl.bioontology.org/ontology/MESH/C060054 http://purl.bioontology.org/ontology/MESH/C090028 http://purl.bioontology.org/ontology/MESH/C090029 http://purl.bioontology.org/ontology/MESH/C076282 http://purl.bioontology.org/ontology/MESH/C058238 http://purl.bioontology.org/ontology/MESH/C095793 http://purl.bioontology.org/ontology/MESH/C095792 http://purl.bioontology.org/ontology/MESH/C074658 http://purl.bioontology.org/ontology/MESH/C024082 http://purl.bioontology.org/ontology/MESH/C029953 http://purl.bioontology.org/ontology/MESH/C059694 http://purl.bioontology.org/ontology/MESH/C059695 http://purl.bioontology.org/ontology/MESH/C059696 http://purl.bioontology.org/ontology/MESH/C113088 http://purl.bioontology.org/ontology/MESH/C113790 http://purl.bioontology.org/ontology/MESH/C069735 http://purl.bioontology.org/ontology/MESH/C059513 http://purl.bioontology.org/ontology/MESH/C080962 http://purl.bioontology.org/ontology/MESH/C080961 http://purl.bioontology.org/ontology/MESH/C040623 http://purl.bioontology.org/ontology/MESH/C019336 http://purl.bioontology.org/ontology/MESH/C011160 http://purl.bioontology.org/ontology/MESH/C078819 http://purl.bioontology.org/ontology/MESH/C113812 http://purl.bioontology.org/ontology/MESH/C065053 http://purl.bioontology.org/ontology/MESH/C479242 http://purl.bioontology.org/ontology/MESH/C096098 http://purl.bioontology.org/ontology/MESH/C019252 http://purl.bioontology.org/ontology/MESH/C028788 http://purl.bioontology.org/ontology/MESH/C585686 http://purl.bioontology.org/ontology/MESH/C067409 http://purl.bioontology.org/ontology/MESH/C055457 http://purl.bioontology.org/ontology/MESH/C483773 http://purl.bioontology.org/ontology/MESH/C073006 http://purl.bioontology.org/ontology/MESH/C062823 http://purl.bioontology.org/ontology/MESH/C039914 http://purl.bioontology.org/ontology/MESH/C114206 http://purl.bioontology.org/ontology/MESH/C047920 http://purl.bioontology.org/ontology/MESH/C048808 http://purl.bioontology.org/ontology/MESH/C048809 http://purl.bioontology.org/ontology/MESH/C522559 http://purl.bioontology.org/ontology/MESH/C529139 http://purl.bioontology.org/ontology/MESH/C076776 http://purl.bioontology.org/ontology/MESH/C055437 http://purl.bioontology.org/ontology/MESH/C532172 http://purl.bioontology.org/ontology/MESH/C052693 http://purl.bioontology.org/ontology/MESH/C078964 http://purl.bioontology.org/ontology/MESH/C055315 http://purl.bioontology.org/ontology/MESH/C058924 http://purl.bioontology.org/ontology/MESH/C058925 http://purl.bioontology.org/ontology/MESH/C002854 http://purl.bioontology.org/ontology/MESH/C051073 http://purl.bioontology.org/ontology/MESH/C000594692 http://purl.bioontology.org/ontology/MESH/C053666 http://purl.bioontology.org/ontology/MESH/C522560 http://purl.bioontology.org/ontology/MESH/C068372 http://purl.bioontology.org/ontology/MESH/C068370 http://purl.bioontology.org/ontology/MESH/C077831 http://purl.bioontology.org/ontology/MESH/C099324 http://purl.bioontology.org/ontology/MESH/C040052 http://purl.bioontology.org/ontology/MESH/C027799 http://purl.bioontology.org/ontology/MESH/C057503 http://purl.bioontology.org/ontology/MESH/C084453 http://purl.bioontology.org/ontology/MESH/C076821 http://purl.bioontology.org/ontology/MESH/C522653
MDA	19880512
MMR	19950608
MN	D13.570.230.500
notation	D015224
PA	D000998 D018894 D000963
prefLabel	Dideoxynucleosides
TERMUI	T044535 T044534 T044532 T044533
TH	NLM (1990) UNK (19XX) NLM (1989)
tui	T114
subClassOf	http://purl.bioontology.org/ontology/MESH/D003853

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/CSP/4000-0366	CRISP	CUI
http://purl.bioontology.org/ontology/MSHFRE/D015224	MSHFRE	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000008043	NDFRT	CUI
http://purl.obolibrary.org/obo/MESH_D015224	BERO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00024069	PMAPP-PMO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3902	OCHV	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0012136	OCHV	LOOM
http://purl.jp/bio/4/id/200906072323789441	IOBC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D13.570.230.500	RH-MESH	LOOM
http://purl.obolibrary.org/obo/OMIT_0016014	OMIT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D015224	RH-MESH	LOOM