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Medical Subject Headings
| Preferred Name | von Willebrand Factor | |
| Synonyms |
Ristocetin-Willebrand Factor Factor VIII-Related Antigen Ristocetin Willebrand Factor Plasma Factor VIII Complex Factor VIIIR RCo Factor VIIIR Ag Factor VIII Related Antigen Factor VIIIR-Ag von Willebrand Protein Factor VIIIR-RCo Ristocetin Cofactor |
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| Definitions |
A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor. |
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| ID |
http://purl.bioontology.org/ontology/MESH/D014841 |
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| altLabel |
Ristocetin-Willebrand Factor Factor VIII-Related Antigen Ristocetin Willebrand Factor Plasma Factor VIII Complex Factor VIIIR RCo Factor VIIIR Ag Factor VIII Related Antigen Factor VIIIR-Ag von Willebrand Protein Factor VIIIR-RCo Ristocetin Cofactor
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| AN |
/ defic = VON WILLEBRAND DISEASE or specific type of Von Willebrand Disease
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|
| AQL |
AA AD AE AG AI AN BI CF CH CL CS DE EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
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|
| cui |
C0042971 C0032114
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|
| DC |
1
|
|
| definition |
A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.
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| DX |
19860101
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| FX |
D020302 D056725 D056729 D056728 D003029 D014842
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|
| HN |
86(76); was see under BLOOD COAGULATION FACTORS 1976-85; FACTOR VIII RELATED ANTIGEN, previously in the Supplementary Chemical File, was mapped to both FACTOR VIII & ANTIGENS 1977-89
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| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
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| Inverse of RB |
0
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|
| Inverse of RO |
http://purl.bioontology.org/ontology/MESH/D020302 http://purl.bioontology.org/ontology/MESH/D056725 http://purl.bioontology.org/ontology/MESH/D056729 http://purl.bioontology.org/ontology/MESH/D056728 |
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| Machine permutation |
86; was see under BLOOD COAGULATION FACTORS 1976-85
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| Mapped from |
http://purl.bioontology.org/ontology/MESH/C029417 http://purl.bioontology.org/ontology/MESH/C044131 http://purl.bioontology.org/ontology/MESH/C509423 http://purl.bioontology.org/ontology/MESH/C568131 http://purl.bioontology.org/ontology/MESH/C067003 http://purl.bioontology.org/ontology/MESH/C069815 http://purl.bioontology.org/ontology/MESH/C121400 http://purl.bioontology.org/ontology/MESH/C473097 http://purl.bioontology.org/ontology/MESH/C112046 http://purl.bioontology.org/ontology/MESH/C050818 |
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| MDA |
19750725
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| MMR |
20090706
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| MN |
D12.776.124.125.920 D23.119.985
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|
| notation |
D014841
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|
| OL |
use FACTOR VIII & ANTIGENS to search FACTOR VIII RELATED ANTIGEN 1977-89
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|
| prefLabel |
von Willebrand Factor
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|
| TERMUI |
T043380 T043384 T043378 T043376 T043382 T043377 T043379 T043381
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|
| TH |
NLM (1990) NLM (1976) UNK (19XX)
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| tui |
T116 T123 T121
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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