Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D014366
http://purl.bioontology.org/ontology/MESH/D014366
Preferred Name

Tryptophan Oxygenase

Definitions
A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is a LIVER-specific enzyme that is the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.
Synonyms
L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing)
TDO Dioxygenase
Tryptophan 2,3-Dioxygenase
Oxygenase, Tryptophan
Tryptophan Pyrrolase
2,3-Dioxygenase, Tryptophan
Dioxygenase, TDO
Tryptophan 2,3 Dioxygenase
Pyrrolase, Tryptophan
Type http://www.w3.org/2002/07/owl#Class
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