loading...| Preferred Name | Neurotransmitter Uptake Inhibitors | |
| Synonyms |
Reuptake Inhibitors, Neurotransmitter Neurotransmitter Reuptake Inhibitors Transmitter Uptake Inhibitors, Neuronal Uptake Inhibitors, Neurotransmitter Inhibitors, Neurotransmitter Reuptake Inhibitors, Neurotransmitter Uptake |
|
| Definitions |
Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D014179 |
|
| altLabel |
Reuptake Inhibitors, Neurotransmitter Neurotransmitter Reuptake Inhibitors Transmitter Uptake Inhibitors, Neuronal Uptake Inhibitors, Neurotransmitter Inhibitors, Neurotransmitter Reuptake Inhibitors, Neurotransmitter Uptake |
|
| AN |
general or unspecified; prefer specific groups or specific drugs; coordinate with specific neurotransmitters /physiol |
|
| AQL |
AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
| cui |
C0040724 |
|
| DC |
1 |
|
| definition |
Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects. |
|
| DX |
19850101 |
|
| HN |
93; WAS TRANSMITTER UPTAKE INHIBITORS, NEURONAL 1985-92; NEUROTRANSMITTER UPTAKE INHIBITORS, INHIBITORS OF NEUROTRANSMITTER UPTAKE & UPTAKE INHIBITORS, NEUROTRANSMITTER were see TRANSMITTER UPTAKE INHIBITORS, NEURONAL 1985-92 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of isa |
http://purl.bioontology.org/ontology/MESH/C081980 http://purl.bioontology.org/ontology/MESH/C078793 http://purl.bioontology.org/ontology/MESH/D006426 http://purl.bioontology.org/ontology/MESH/C012102 http://purl.bioontology.org/ontology/MESH/D000657 |
|
| Inverse of RB |
0 |
|
| Machine permutation |
93; was TRANSMITTER UPTAKE INHIBITORS, NEURONAL 1985-92; NEUROTRANSMITTER UPTAKE INHIBITORS, INHIBITORS OF NEUROTRANSMITTER UPTAKE & UPTAKE INHIBITORS, NEUROTRANSMITTER were see TRANSMITTER UPTAKE INHIBITORS, NEURONAL 1985-92 |
|
| MDA |
19840501 |
|
| MMR |
20190524 |
|
| MN |
D27.505.519.562.437 D27.505.696.577.600 D27.505.519.625.600 |
|
| notation |
D014179 |
|
| OL |
use NEUROTRANSMITTER UPTAKE INHIBITORS to search TRANSMITTER UPTAKE INHIBITORS, NEURONAL; INHIBITORS OF NEUROTRANSMITTER UPTAKE & UPTAKE INHIBITORS, NEUROTRANSMITTER 1985-92 |
|
| prefLabel |
Neurotransmitter Uptake Inhibitors |
|
| TERMUI |
T041538 T041542 T041541 T041540 T041539 |
|
| TH |
NLM (1993) UNK (19XX) NLM (1985) |
|
| tui |
T121 |
|
| subClassOf |