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Last uploaded: January 31, 2024

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Preferred Name	Thymidylate Synthase
Synonyms	Thymidylate Synthetase 5,10-Methylenetetrahydrofolate:dUMP C-methyltransferase Synthetase, Thymidylate Synthase, Thymidylate
Definitions	An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of thymidine triphosphate. (From Dorland, 27th ed) EC 2.1.1.45.
ID	http://purl.bioontology.org/ontology/MESH/D013940
altLabel	Thymidylate Synthetase 5,10-Methylenetetrahydrofolate:dUMP C-methyltransferase Synthetase, Thymidylate Synthase, Thymidylate
AQL	AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui	C0040085
DC	1
definition	An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of thymidine triphosphate. (From Dorland, 27th ed) EC 2.1.1.45.
DX	19860101
HN	1998; see METHYLTRANSFERASES 1975-1985
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	EC 2.1.1.45
Machine permutation	1998; see METHYLTRANSFERASES 1975-1985, see THYMIDYLATE SYNTHETASE 1985-1997
Mapped from	http://purl.bioontology.org/ontology/MESH/C056930 http://purl.bioontology.org/ontology/MESH/C000600377 http://purl.bioontology.org/ontology/MESH/C075106
MDA	19990101
MMR	20190701
MN	D08.811.913.555.500.862
notation	D013940
prefLabel	Thymidylate Synthase
RR	9031-61-2 (CAS RN)
TERMUI	T040895 T040894
TH	NLM (1973) NLM (1998)
tui	T116 T126
subClassOf	http://purl.bioontology.org/ontology/MESH/D008780

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/SCTSPA/6937006	SCTSPA	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000168188	NDFRT	CUI
http://purl.bioontology.org/ontology/CSP/2963-9288	CRISP	CUI
http://purl.bioontology.org/ontology/SNMI/F-68268	SNMI	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/6937006	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/MSHFRE/D013940	MSHFRE	CUI
http://purl.obolibrary.org/obo/OMIT_0014785	OMIT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013940	RH-MESH	LOOM
http://purl.obolibrary.org/obo/NCIT_C17199	BERO	LOOM
http://purl.obolibrary.org/obo/dinto_0117	DINTO	LOOM
http://purl.uniprot.org/uniprot/P04818	FTC	LOOM
http://purl.jp/bio/4/id/200906089162113981	IOBC	LOOM
http://purl.obolibrary.org/obo/dinto_3954	DINTO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#12241	OCHV	LOOM
http://purl.obolibrary.org/obo/dinto_0910	DINTO	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17199	NCIT	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0040085	OCHV	LOOM
http://purl.bioontology.org/ontology/CSP/2963-9288	CRISP	LOOM
http://purl.bioontology.org/ontology/SNMI/F-68268	SNMI	LOOM
http://purl.obolibrary.org/obo/dinto_1622	DINTO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00020790	PMAPP-PMO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D08.811.913.555.500.862	RH-MESH	LOOM
http://id.nlm.nih.gov/mesh/D013940	MDM	LOOM
http://www.co-ode.org/ontologies/galen#ThymidylateSynthase	GALEN	LOOM
http://purl.obolibrary.org/obo/MESH_D013940	BERO	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/6937006	SNOMEDCT	LOOM
http://purl.obolibrary.org/obo/dinto_3510	DINTO	LOOM
http://purl.obolibrary.org/obo/PR_000016876	PR	LOOM
http://purl.obolibrary.org/obo/PR_000016876	INBANCIDO	LOOM
http://purl.obolibrary.org/obo/PR_000016876	CIDO	LOOM
http://purl.obolibrary.org/obo/PR_000016876	NIFSTD	LOOM