loading...| Preferred Name | Farnesyl-Diphosphate Farnesyltransferase | |
| Synonyms |
Farnesyldiphosphate-Farnesyldiphosphate Farnesyltransferase Presqualene-Diphosphate Synthase Synthase, Squalene Transferase, FPP-FPP Farnesyl Squalene Synthase Farnesyldiphosphate Farnesyldiphosphate Farnesyltransferase Farnesyltransferase, Farnesyldiphosphate-Farnesyldiphosphate Squalene Synthetase FPP-FPP Farnesyl Transferase Farnesyl Diphosphate Farnesyltransferase Farnesyltransferase, Farnesyl-Diphosphate Farnesyl Transferase, FPP-FPP Presqualene Diphosphate Synthase Synthetase, Squalene Synthase, Presqualene-Diphosphate FPP FPP Farnesyl Transferase |
|
| Definitions |
The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it catalyzes the synthesis of SQUALENE from farnesyl pyrophosphate via the intermediate PRESQUALENE PYROPHOSPHATE. This enzyme is also a critical branch point enzyme in the biosynthesis of ISOPRENOIDS that is thought to regulate the flux of isoprene intermediates through the sterol pathway. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D013186 |
|
| altLabel |
Farnesyldiphosphate-Farnesyldiphosphate Farnesyltransferase Presqualene-Diphosphate Synthase Synthase, Squalene Transferase, FPP-FPP Farnesyl Squalene Synthase Farnesyldiphosphate Farnesyldiphosphate Farnesyltransferase Farnesyltransferase, Farnesyldiphosphate-Farnesyldiphosphate Squalene Synthetase FPP-FPP Farnesyl Transferase Farnesyl Diphosphate Farnesyltransferase Farnesyltransferase, Farnesyl-Diphosphate Farnesyl Transferase, FPP-FPP Presqualene Diphosphate Synthase Synthetase, Squalene Synthase, Presqualene-Diphosphate FPP FPP Farnesyl Transferase |
|
| AQL |
AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
|
| cui |
C0597790 |
|
| DC |
1 |
|
| definition |
The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it catalyzes the synthesis of SQUALENE from farnesyl pyrophosphate via the intermediate PRESQUALENE PYROPHOSPHATE. This enzyme is also a critical branch point enzyme in the biosynthesis of ISOPRENOIDS that is thought to regulate the flux of isoprene intermediates through the sterol pathway. |
|
| DX |
19910101 |
|
| HN |
2006(1975) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
EC 2.5.1.21 |
|
| Machine permutation |
2006; see OXIDOREDUCTASES 1975-1990; FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE was indexed under OXIDOREDUCTASES & SQUALENE SYNTHETASE 1998-2001 |
|
| Mapped from | ||
| MDA |
19741119 |
|
| MMR |
20090713 |
|
| MN |
D08.811.913.225.431 |
|
| notation |
D013186 |
|
| prefLabel |
Farnesyl-Diphosphate Farnesyltransferase |
|
| TERMUI |
T327172 T327171 T327174 T528461 T038733 T327173 |
|
| TH |
NLM (2004) NLM (1975) NLM (2006) |
|
| tui |
T116 T126 |
|
| subClassOf |