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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D013148
http://purl.bioontology.org/ontology/MESH/D013148
|
|---|---|
| Preferred Name | Spironolactone |
| Definitions |
A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
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| Synonyms |
Aquareduct
SC-9420
Spirobeta
Spironone
SC 9420
Spirolactone
Novo-Spiroton
Verospiron
Flumach
Spiro Von Ct
Verospirone
Espironolactona Mundogen
Veroshpiron
Spiro L.U.T.
Spirospare
Espironolactona Alter
Von Ct, Spiro
Ct, Spiro Von
Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)-
Spiractin
Practon
Spirolang
Spirono-Isis
Frumikal
Novo Spiroton
NovoSpiroton
Spirogamma
Aldactone A
Jenaspiron
Spirono Isis
Duraspiron
SC9420
Aldactone
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827) |
|---|---|
| altLabel |
Aquareduct
SC-9420
Spirobeta
Spironone
SC 9420
Spirolactone
Novo-Spiroton
Verospiron
Flumach
Spiro Von Ct
Verospirone
Espironolactona Mundogen
Veroshpiron
Spiro L.U.T.
Spirospare
Espironolactona Alter
Von Ct, Spiro
Ct, Spiro Von
Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)-
Spiractin
Practon
Spirolang
Spirono-Isis
Frumikal
Novo Spiroton
NovoSpiroton
Spirogamma
Aldactone A
Jenaspiron
Spirono Isis
Duraspiron
SC9420
Aldactone
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|
| prefLabel | Spironolactone
|
| TH |
NLM (1996)
US
UK
CA
NLM (1990)
FDA SRS (2014)
ES
UNK (19XX)
INN (19XX)
DE
AU
USP (19XX)
BAN (19XX)
FR
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|
| notation | D013148
|
| RR | 52-01-7 (Spironolactone)
|
| DX | 19660101
|
| MN |
D04.210.500.745.745.855
D02.540.679
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| PA |
D004232
D000451
|
| MMR | 20170524
|
| Mapped from |
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|
| AQL | AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
|
| subClassOf | |
| Semantic type UMLS property | |
| Inverse of RB |
27O7W4T232
0
|
| LT | TRD
|
| DC | 1
|
| MDA | 19990101
|
| type | |
| tui |
T109
T121
|
| cui |
C0592135
C0600340
C1564174
C1564159
C0701471
C0591054
C1564157
C1564173
C1564166
C1564162
C1564160
C1564194
C1564193
C1564163
C1564156
C1564155
C1564154
C0037982
C1564161
C1564165
C1564158
C0701468
C1564164
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|
| isa | |
| Inverse of AQ |
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|
| TERMUI |
T000912891
T618540
T618544
T618536
T618532
T618534
T618592
T618590
T038655
T618542
T618538
T618733
T618524
T000912890
T038656
T038653
T038654
T618528
T038658
T038659
T038652
T038657
T618594
T618548
T618731
T618530
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| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |