Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D013004
http://purl.bioontology.org/ontology/MESH/D013004
Preferred Name

Somatostatin

Definitions
A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.
Synonyms
Somatostatin 14
Somatotropin Release-Inhibiting Hormone
Somatotropin Release Inhibiting Hormone
Somatotropin Release Inhibiting Factor
Stilamin
Somatostatin-14
Somatostatin, Cyclic
SRIH-14
Somatofalk
Somatotropin Release-Inhibiting Factor
Cyclic Somatostatin
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Type http://www.w3.org/2002/07/owl#Class
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