Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D012194 http://purl.bioontology.org/ontology/MESH/D012194
Preferred Name	RNA-Directed DNA Polymerase
Definitions	An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and by certain retrovirus-like elements. EC 2.7.7.49.
Synonyms	DNA Polymerase, RNA-Dependent RNA-Dependent DNA Polymerase RNA Directed DNA Polymerase RNA Dependent DNA Polymerase Deoxynucleotide-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) RNA Transcriptase Revertase Reverse Transcriptase DNA Polymerase, RNA Directed DNA Polymerase, RNA-Directed
Type	http://www.w3.org/2002/07/owl#Class

definition	An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and by certain retrovirus-like elements. EC 2.7.7.49.
altLabel	DNA Polymerase, RNA-Dependent RNA-Dependent DNA Polymerase RNA Directed DNA Polymerase RNA Dependent DNA Polymerase Deoxynucleotide-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) RNA Transcriptase Revertase Reverse Transcriptase DNA Polymerase, RNA Directed DNA Polymerase, RNA-Directed See more See less
prefLabel	RNA-Directed DNA Polymerase
EC	antagonists & inhibitors:Reverse Transcriptase Inhibitors
Machine permutation	96; was REVERSE TRANSCRIPTASE 1973-95
HN	96; was REVERSE TRANSCRIPTASE 1972-95 (Prov 1972)
Mapped from	http://purl.bioontology.org/ontology/MESH/C513205 http://purl.bioontology.org/ontology/MESH/C101001 http://purl.bioontology.org/ontology/MESH/C099686 http://purl.bioontology.org/ontology/MESH/C496084 http://purl.bioontology.org/ontology/MESH/C531246 http://purl.bioontology.org/ontology/MESH/C454879 http://purl.bioontology.org/ontology/MESH/C099785 http://purl.bioontology.org/ontology/MESH/C545659 http://purl.bioontology.org/ontology/MESH/C066564 http://purl.bioontology.org/ontology/MESH/C067164 http://purl.bioontology.org/ontology/MESH/C496854 http://purl.bioontology.org/ontology/MESH/C494024 See more See less
type	http://www.w3.org/2002/07/owl#Class
tui	T116 T126
TERMUI	T036296 T036295 T036293 T036291 T036294 T036292 See more See less
TH	NLM (1996) UNK (19XX) NLM (1972)
MMR	20200622
notation	D012194
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D048348 http://purl.bioontology.org/ontology/MESH/D015684 http://purl.bioontology.org/ontology/MESH/D000094405 http://purl.bioontology.org/ontology/MESH/D020133
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T126 http://purl.bioontology.org/ontology/STY/T116
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
DX	19730101
cui	C0035379
DC	1
MN	D08.811.913.696.445.308.300.750 D12.776.964.970.600.850.375.750 D12.776.964.775.375.750 D12.776.964.900.750.500.750
AQL	AD AE AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
Inverse of RB	EC 2.7.7.49
MDA	19990101
subClassOf	http://purl.bioontology.org/ontology/MESH/D004259 http://purl.bioontology.org/ontology/MESH/D015684

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