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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D012172
http://purl.bioontology.org/ontology/MESH/D012172
|
|---|---|
| Preferred Name | Retinaldehyde |
| Definitions |
A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer.
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| Synonyms |
3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-Nonatetraenal
Vitamin A Aldehyde
all trans Retinal
Retinyl Aldehydde
11 cis Retinal
Axerophthal
Aldehydde, Retinyl
all-trans-Retinal
Retinene
11-trans-Retinal
Retinal
11 trans Retinal
Aldehyde, Vitamin A
11-cis-Retinal
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer. |
|---|---|
| altLabel |
3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-Nonatetraenal
Vitamin A Aldehyde
all trans Retinal
Retinyl Aldehydde
11 cis Retinal
Axerophthal
Aldehydde, Retinyl
all-trans-Retinal
Retinene
11-trans-Retinal
Retinal
11 trans Retinal
Aldehyde, Vitamin A
11-cis-Retinal
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|
| prefLabel | Retinaldehyde
|
| Machine permutation | 91; was see under RETINOIDS 1984-90; was see under VITAMIN A 1968-83
|
| HN | 91(75); was see under RETINOIDS 1984-90; was see under VITAMIN A 1968-83
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| Mapped from |
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| type | |
| tui |
T109
T123
T127
T121
|
| TERMUI |
T001104346
T036225
T001096825
T036228
T001096823
T001096816
T036223
T036226
T036224
T036227
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| TH |
NLM (1975)
FDA SRS (2014)
UNK (19XX)
NLM (2022)
|
| MMR | 20210707
|
| notation | D012172
|
| Semantic type UMLS property | |
| RR | 116-31-4 (Retinaldehyde)
|
| Inverse of AQ |
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| DX | 19910101
|
| cui |
C0035331
C0085717
|
| DC | 1
|
| MN |
D02.455.849.291.605
D02.455.426.392.368.367.379.249.700.690
D02.047.850
D02.455.326.271.665.202.495.690
D02.455.849.131.495.690
D23.767.261.700.690
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| AN | /biosyn /physiol permitted
|
| AQL | AA AD AE AG AI AN BI BL CF CH CL CS DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR
|
| Inverse of RB |
0
RR725D715M
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| OL | search VITAMIN A 1968-74
|
| MDA | 19990101
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |