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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D011697
http://purl.bioontology.org/ontology/MESH/D011697
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|---|---|
| Preferred Name | Purpura, Thrombotic Thrombocytopenic |
| Definitions |
An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE. Mutations in the ADAMTS13 PROTEIN gene have been identified in familial cases.
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| Synonyms |
Thrombotic Thrombopenic Purpura
Purpura, Thrombotic Thrombopenic
Familial Thrombotic Microangiopathy
Thrombotic Thrombocytopenic Purpura, Congenital
Familial Thrombotic Thrombocytopenic Purpura
Moschcowitz Disease
Thrombocytopenic Purpura, Thrombotic
Schulman Upshaw Syndrome
Microangiopathic Hemolytic Anemia, Congenital
Thrombopenic Purpura, Thrombotic
Thrombotic Thrombocytopenic Purpura
Upshaw Factor, Deficiency of
Moschkowitz Disease
Microangiopathy, Familial Thrombotic
Familial Thrombotic Thrombocytopenia Purpura
Schulman-Upshaw Syndrome
Upshaw-Schulman Syndrome
Congenital Thrombotic Thrombocytopenic Purpura
Upshaw Schulman Syndrome
Thrombotic Microangiopathy, Familial
Thrombotic Thrombocytopenic Purpura, Familial
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE. Mutations in the ADAMTS13 PROTEIN gene have been identified in familial cases. |
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| altLabel |
Thrombotic Thrombopenic Purpura
Purpura, Thrombotic Thrombopenic
Familial Thrombotic Microangiopathy
Thrombotic Thrombocytopenic Purpura, Congenital
Familial Thrombotic Thrombocytopenic Purpura
Moschcowitz Disease
Thrombocytopenic Purpura, Thrombotic
Schulman Upshaw Syndrome
Microangiopathic Hemolytic Anemia, Congenital
Thrombopenic Purpura, Thrombotic
Thrombotic Thrombocytopenic Purpura
Upshaw Factor, Deficiency of
Moschkowitz Disease
Microangiopathy, Familial Thrombotic
Familial Thrombotic Thrombocytopenia Purpura
Schulman-Upshaw Syndrome
Upshaw-Schulman Syndrome
Congenital Thrombotic Thrombocytopenic Purpura
Upshaw Schulman Syndrome
Thrombotic Microangiopathy, Familial
Thrombotic Thrombocytopenic Purpura, Familial
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| prefLabel | Purpura, Thrombotic Thrombocytopenic
|
| Machine permutation | 1986; see PURPURA, THROMBOTIC THROMBOPENIC 1965-1985
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| HN | 1986; use PURPURA, THROMBOTIC THROMBOPENIC 1965-1985
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| Mapped from | |
| type | |
| tui | T047
|
| TERMUI |
T842588
T034585
T843443
T679350
T034586
T750375
T812539
T781563
T679352
T679351
T034587
T781564
T679329
T781565
T750374
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| TH |
OMIM (2013)
NLM (2008)
NLM (2012)
NLM (1992)
UNK (19XX)
NLM (2010)
GHR (2014)
NLM (1964)
NLM (2014)
ORD (2010)
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| MMR | 20230226
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| notation | D011697
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| Semantic type UMLS property | |
| Inverse of AQ |
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| DX | 19650101
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| cui |
C1956258
C1268935
C0034155
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| DC | 1
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| MN |
C15.378.100.802.687.680
C15.378.925.850
C23.550.414.950.687.680
C15.378.243.937.925.750.680
C15.378.140.855.925.750.680
C23.888.885.687.687.680
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| AQL | BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI
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| MDA | 19990101
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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