Medical Subject Headings

Last uploaded: January 31, 2024

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Preferred Name	Protamines
Synonyms	Protamine Sulfate Chloride, Protamine Sulfate, Protamine Protamine Protamine Chloride
Definitions	A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692)
ID	http://purl.bioontology.org/ontology/MESH/D011479
altLabel	Protamine Sulfate Chloride, Protamine Sulfate, Protamine Protamine Protamine Chloride
AN	heparin antag
AQL	AD AE AG AI AN BL CF CH CL CS DE EC GE HI IM IP ME PD PK PO RE SD ST TO TU UL UR
cui	C0033600 C0033602 C0033603
DC	1
definition	A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692)
DX	19660101
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	0
isa	http://purl.bioontology.org/ontology/MESH/D006494
Mapped from	http://purl.bioontology.org/ontology/MESH/C029997 http://purl.bioontology.org/ontology/MESH/C082073 http://purl.bioontology.org/ontology/MESH/C052196 http://purl.bioontology.org/ontology/MESH/C044167 http://purl.bioontology.org/ontology/MESH/C047696 http://purl.bioontology.org/ontology/MESH/C015786 http://purl.bioontology.org/ontology/MESH/C080176 http://purl.bioontology.org/ontology/MESH/C074156 http://purl.bioontology.org/ontology/MESH/C074157 http://purl.bioontology.org/ontology/MESH/C046533 http://purl.bioontology.org/ontology/MESH/C109762 http://purl.bioontology.org/ontology/MESH/C017278 http://purl.bioontology.org/ontology/MESH/C010167 http://purl.bioontology.org/ontology/MESH/C068621 http://purl.bioontology.org/ontology/MESH/C069925 http://purl.bioontology.org/ontology/MESH/C049117 http://purl.bioontology.org/ontology/MESH/C052908 http://purl.bioontology.org/ontology/MESH/C050556 http://purl.bioontology.org/ontology/MESH/C048529 http://purl.bioontology.org/ontology/MESH/C015513 http://purl.bioontology.org/ontology/MESH/C070831 http://purl.bioontology.org/ontology/MESH/C087063 http://purl.bioontology.org/ontology/MESH/C053431 http://purl.bioontology.org/ontology/MESH/C103762 http://purl.bioontology.org/ontology/MESH/C513176 http://purl.bioontology.org/ontology/MESH/C513174 http://purl.bioontology.org/ontology/MESH/C025098 http://purl.bioontology.org/ontology/MESH/C503325 http://purl.bioontology.org/ontology/MESH/C503324 http://purl.bioontology.org/ontology/MESH/C083061 http://purl.bioontology.org/ontology/MESH/C053106 http://purl.bioontology.org/ontology/MESH/C065206 http://purl.bioontology.org/ontology/MESH/C093295 http://purl.bioontology.org/ontology/MESH/C001472 http://purl.bioontology.org/ontology/MESH/C110077 http://purl.bioontology.org/ontology/MESH/C103098 http://purl.bioontology.org/ontology/MESH/C029828 http://purl.bioontology.org/ontology/MESH/C029829 http://purl.bioontology.org/ontology/MESH/C030101 http://purl.bioontology.org/ontology/MESH/C081221 http://purl.bioontology.org/ontology/MESH/C081220
MDA	19990101
MMR	20200527
MN	D12.776.664.750 D12.776.660.750
notation	D011479
PA	D006494
prefLabel	Protamines
TERMUI	T033904 T033903 T000999804 T033902
TH	NLM (1966) UNK (19XX) NLM (2021)
tui	T116 T123 T130 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D009698 http://purl.bioontology.org/ontology/MESH/D009687

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/NDFRT/N0000145846	NDFRT	CUI
http://purl.bioontology.org/ontology/RXNORM/8826	RXNORM	CUI
http://purl.bioontology.org/ontology/RXNORM/8825	RXNORM	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000178966	NDFRT	CUI
http://purl.bioontology.org/ontology/NDDF/002093	NDDF	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/64520006	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SNMI/C-A6710	SNMI	CUI
http://purl.bioontology.org/ontology/SCTSPA/64520006	SCTSPA	CUI
http://purl.bioontology.org/ontology/VANDF/4017458	VANDF	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148002	NDFRT	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/372630008	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/MSHFRE/D011479	MSHFRE	CUI
http://purl.bioontology.org/ontology/SCTSPA/350083007	SCTSPA	CUI
http://purl.bioontology.org/ontology/CSP/2447-3500	CRISP	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000006896	NDFRT	CUI
http://purl.bioontology.org/ontology/NDDF/006047	NDDF	CUI
http://purl.bioontology.org/ontology/VANDF/4019917	VANDF	CUI
http://purl.bioontology.org/ontology/LNC/LP15134-7	LOINC	CUI
http://purl.bioontology.org/ontology/SCTSPA/372630008	SCTSPA	CUI
http://purl.bioontology.org/ontology/ATC/V03AB14	ATC	CUI
http://purl.bioontology.org/ontology/RCD/x01GX	RCD	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/350083007	SNOMEDCT	CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.664.750	RH-MESH	LOOM
http://purl.bioontology.org/ontology/RXNORM/8826	RXNORM	LOOM
http://localhost/plosthes.2017-1#5219	PLOSTHES	LOOM
http://purl.obolibrary.org/obo/DRON_00011914	PDRO	LOOM
http://purl.obolibrary.org/obo/DRON_00011914	DRON	LOOM
http://purl.obolibrary.org/obo/OMIT_0012425	OMIT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D011479	RH-MESH	LOOM
http://purl.obolibrary.org/obo/MESH_D011479	BERO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00023634	PMAPP-PMO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.660.750	RH-MESH	LOOM