Preferred Name | Pro-Opiomelanocortin | |
Synonyms |
ACTH beta Lipotropin Precursor Endorphin ACTH Precursor Pro Opiocortin Pro Opio Melanocortin Pro Opiomelanocortin ACTH-beta-Lipotropin Precursor Pre-POMC Proopiocortin Pre-pro-opiocortin Endorphin-ACTH Precursor Pro ACTH Endorphin Opiocortin Corticotropin-beta-Lipotropin Precursor Pro-ACTH-Endorphin Proopiomelanocortin Preproopiomelanocortin Opiomelanocortin, pro- POMC Pre pro opiocortin Corticotropin beta Lipotropin Precursor ACTH Endorphin Precursor Pro-Opiocortin Pro-Opio-Melanocortin ACTH-Endorphin Precursor Pre POMC |
|
Definitions |
A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP). |
|
ID |
http://purl.bioontology.org/ontology/MESH/D011333 |
|
altLabel |
ACTH beta Lipotropin Precursor Endorphin ACTH Precursor Pro Opiocortin Pro Opio Melanocortin Pro Opiomelanocortin ACTH-beta-Lipotropin Precursor Pre-POMC Proopiocortin Pre-pro-opiocortin Endorphin-ACTH Precursor Pro ACTH Endorphin Opiocortin Corticotropin-beta-Lipotropin Precursor Pro-ACTH-Endorphin Proopiomelanocortin Preproopiomelanocortin Opiomelanocortin, pro- POMC Pre pro opiocortin Corticotropin beta Lipotropin Precursor ACTH Endorphin Precursor Pro-Opiocortin Pro-Opio-Melanocortin ACTH-Endorphin Precursor Pre POMC |
|
AQL |
AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
|
cui |
C0033195 C0071826 C0069575 |
|
DC |
1 |
|
definition |
A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP). |
|
DX |
19850101 |
|
HN |
1985 |
|
Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
Inverse of RB |
76775-14-9 78321-08-1 66796-54-1 |
|
Machine permutation |
1985; PRE-PRO-OPIOCORTIN was indexed under PRO-OPIOMELANOCORTIN & PROTEIN PRECURSORS 1980-2007; OPIOCORTIN was indexed under PRO-OPIOMELANOCORTIN 1987-2007 |
|
Mapped from |
http://purl.bioontology.org/ontology/MESH/C049531 http://purl.bioontology.org/ontology/MESH/C565726 http://purl.bioontology.org/ontology/MESH/C553466 http://purl.bioontology.org/ontology/MESH/C104706 http://purl.bioontology.org/ontology/MESH/C421923 http://purl.bioontology.org/ontology/MESH/C421924 http://purl.bioontology.org/ontology/MESH/C031562 http://purl.bioontology.org/ontology/MESH/C028182 http://purl.bioontology.org/ontology/MESH/C048786 http://purl.bioontology.org/ontology/MESH/C064114 http://purl.bioontology.org/ontology/MESH/C039934 http://purl.bioontology.org/ontology/MESH/C037670 |
|
MDA |
19840530 |
|
MMR |
20151124 |
|
MN |
D06.472.699.631.525.600 D12.644.548.691.525.690 D12.776.631.650.405.935 D12.644.400.400.935 D12.776.811.800 D06.472.699.327.935 D12.644.548.365.935 |
|
notation |
D011333 |
|
prefLabel |
Pro-Opiomelanocortin |
|
RR |
76775-14-9 78321-08-1 |
|
TERMUI |
T033400 T033408 T175718 T033399 T114909 T033401 T033402 T033409 T033404 T033403 T033407 T033405 T686011 T114911 T033406 |
|
TH |
NLM (2008) UNK (19XX) NLM (1985) |
|
tui |
T125 T116 T121 |
|
subClassOf |
http://purl.bioontology.org/ontology/MESH/D011498 |