Medical Subject Headings

Last uploaded: January 16, 2025
Id http://purl.bioontology.org/ontology/MESH/D011328
http://purl.bioontology.org/ontology/MESH/D011328
Preferred Name

Prions

Definitions
Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.
Synonyms
Encephalopathy Virus, Mink
Mink Encephalopathy Virus
Prion
Type http://www.w3.org/2002/07/owl#Class
Delete Subject Author Type Created
No notes to display