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January 16, 2025
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Id | http://purl.bioontology.org/ontology/MESH/D011328
http://purl.bioontology.org/ontology/MESH/D011328
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Preferred Name | Prions |
Definitions |
Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.
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Synonyms |
Encephalopathy Virus, Mink
Mink Encephalopathy Virus
Prion
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL. |
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altLabel |
Encephalopathy Virus, Mink
Mink Encephalopathy Virus
Prion
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prefLabel |
Prions
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TH |
NLM (1993)
NLM (2021)
NLM (1986)
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notation |
D011328
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DX |
19860101
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Machine permutation |
86; MINK ENCEPHALOPATHY VIRUS was heading 1991-92, was see under VERTEBRATE VIRUSES, UNCLASSIFIED (now VIRUSES, UNCLASSIFIED) 1975-90; TRANSMISSIBLE ENCEPHALOPATHY VIRUS OF MINK was see MINK ENCEPHALOPATHY VIRUS 1975-92
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MN |
D12.776.785
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MMR |
20200527
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Mapped from |
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AQL |
AD AE AG AI AN BI BL CF CH CL CS DE EC GE HI IM IP ME PD PH PK PO PY RE SD ST TO TU UL UR
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HN |
86; MINK ENCEPHALOPATHY VIRUS was heading 1991-92, was see under VERTEBRATE VIRUSES, UNCLASSIFIED (now VIRUSES, UNCLASSIFIED) 1975-90; TRANSMISSIBLE ENCEPHALOPATHY VIRUS OF MINK was see MINK ENCEPHALOPATHY VIRUS 1975-92
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subClassOf | |
Semantic type UMLS property | |
Inverse of RB |
0
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DC |
1
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MDA |
19850510
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Inverse of RO | |
type | |
tui |
T116
T005
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cui |
C0033164
C0026181
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Inverse of AQ |
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OL |
use PRIONS to search MINK ENCEPHALOPATHY VIRUS & TRANSMISSIBLE ENCEPHALOPATHY VIRUS OF MINK 1975-92
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TERMUI |
T000999030
T033389
T033390
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