Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D011065 http://purl.bioontology.org/ontology/MESH/D011065
Preferred Name	Poly(ADP-ribose) Polymerases
Definitions	Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up a linear or branched homopolymer of repeating ADP-ribose units i.e., POLY ADENOSINE DIPHOSPHATE RIBOSE.
Synonyms	Poly(ADPR) Polymerase Poly ADP Ribose Polymerase Poly ADP Ribose Transferase Poly(ADP-ribose) Polymerase ADP-Ribosyltransferase (Polymerizing) Poly(ADP-Ribose) Synthase NAD+:poly(adenosine diphosphate D-ribose)-acceptor ADP-D-ribosyltransferase Polymerase, PARP Synthase, Poly ADP-Ribose Poly(ADP-Ribose) Transferase PARP Polymerase Poly ADP Ribose Synthase Poly(ADPribose) Polymerase Poly ADP-Ribose Synthase See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up a linear or branched homopolymer of repeating ADP-ribose units i.e., POLY ADENOSINE DIPHOSPHATE RIBOSE.
altLabel	Poly(ADPR) Polymerase Poly ADP Ribose Polymerase Poly ADP Ribose Transferase Poly(ADP-ribose) Polymerase ADP-Ribosyltransferase (Polymerizing) Poly(ADP-Ribose) Synthase NAD+:poly(adenosine diphosphate D-ribose)-acceptor ADP-D-ribosyltransferase Polymerase, PARP Synthase, Poly ADP-Ribose Poly(ADP-Ribose) Transferase PARP Polymerase Poly ADP Ribose Synthase Poly(ADPribose) Polymerase Poly ADP-Ribose Synthase See more See less
prefLabel	Poly(ADP-ribose) Polymerases
EC	antagonists & inhibitors:Poly(ADP-ribose) Polymerase Inhibitors
Machine permutation	2003; see NAD+ ADP-RIBOSYLTRANSFERASE 1992-2002, see POLY ADP RIBOSE POLYMERASE 1977-1991, see NAD NUCLEOSIDASE 1975-1976
HN	2003 (1977); use NAD NUCLEOSIDASE 1975-1976
Mapped from	http://purl.bioontology.org/ontology/MESH/C483041 http://purl.bioontology.org/ontology/MESH/C000594530 http://purl.bioontology.org/ontology/MESH/C459820 http://purl.bioontology.org/ontology/MESH/C000716487 http://purl.bioontology.org/ontology/MESH/C000596430 http://purl.bioontology.org/ontology/MESH/C559916 http://purl.bioontology.org/ontology/MESH/C576117 http://purl.bioontology.org/ontology/MESH/C529384 http://purl.bioontology.org/ontology/MESH/C000625488 http://purl.bioontology.org/ontology/MESH/C480979 http://purl.bioontology.org/ontology/MESH/C418133 http://purl.bioontology.org/ontology/MESH/C487881 http://purl.bioontology.org/ontology/MESH/C000727117 http://purl.bioontology.org/ontology/MESH/C522628 http://purl.bioontology.org/ontology/MESH/C000625018 http://purl.bioontology.org/ontology/MESH/C584083 http://purl.bioontology.org/ontology/MESH/C000594851 http://purl.bioontology.org/ontology/MESH/C499627 http://purl.bioontology.org/ontology/MESH/C000605039 http://purl.bioontology.org/ontology/MESH/C000712895 http://purl.bioontology.org/ontology/MESH/C557783 http://purl.bioontology.org/ontology/MESH/C000611446 http://purl.bioontology.org/ontology/MESH/C449359 See more See less
type	http://www.w3.org/2002/07/owl#Class
tui	T116 T126
TERMUI	T481789 T475372 T032535 T475403 T032536 T475402 T032537 T481790 T032538 T471640 T032541 See more See less
TH	NLM (1999) NLM (1994) NLM (1992) UNK (19XX) NLM (2003)
MMR	20190701
notation	D011065
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D011064 http://purl.bioontology.org/ontology/MESH/D000074747
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T126 http://purl.bioontology.org/ontology/STY/T116
RR	58319-92-9 (CAS RN)
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
FX	D000074747
DX	19860101
cui	C0032405
DC	1
MN	D08.811.913.400.725.115.690
AQL	AD AE AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
Inverse of RB	EC 2.4.2.30
MDA	20011231
subClassOf	http://purl.bioontology.org/ontology/MESH/D036002

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