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Last uploaded:
January 16, 2025
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| Id | http://purl.bioontology.org/ontology/MESH/D011034
http://purl.bioontology.org/ontology/MESH/D011034
|
|---|---|
| Preferred Name | Podophyllotoxin |
| Definitions |
A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.
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| Synonyms |
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a beta,9 alpha))-Isomer
Podofilm
Epipodophyllotoxin
Podocon-25
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 alpha))-Isomer
Podophyllotoxin, (5R-(5 alpha,5a beta,8a alpha,9 beta))-Isomer
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 beta))-Isomer
Wartec
Warticon
Condylox
Condyline
CPH86
Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9alpha))-
Podofilox
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. |
|---|---|
| altLabel |
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a beta,9 alpha))-Isomer
Podofilm
Epipodophyllotoxin
Podocon-25
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 alpha))-Isomer
Podophyllotoxin, (5R-(5 alpha,5a beta,8a alpha,9 beta))-Isomer
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 beta))-Isomer
Wartec
Warticon
Condylox
Condyline
CPH86
Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9alpha))-
Podofilox
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|
| prefLabel |
Podophyllotoxin
|
| TH |
US
UK
NL
NLM (1999)
CA
FDA SRS (2014)
ES
NLM (1992)
UNK (19XX)
DE
AU
NLM (1998)
BAN (19XX)
USAN (1989)
FR
IE
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|
| notation |
D011034
|
| RR |
518-28-5 (Podophyllotoxin)
477-47-4 ((5R-(5 alpha,5a alpha,8a alpha,9 alpha))-isomer)
4375-07-9 ((5R-(5 alpha,5a beta,8a alpha,9 beta))-isomer)
4375-06-8 ((5R-(5 alpha,5a alpha,8a alpha,9 beta))-isomer)
55568-79-1 ((5R-(5 alpha,5a alpha,8a beta,9 alpha))-isomer)
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| DX |
19730101
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| Machine permutation |
73; EPIPODOPHYLLOTOXIN was see under PODOPHYLLOTOXIN 1975
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| MN |
D02.455.426.559.389.140.450.777
D02.455.426.559.847.638.960.675
D04.615.638.960.675
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| PA |
D000972
D007641
D050257
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| MMR |
20160701
|
| Mapped from |
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| AQL |
AA AD AE AG AI AN BI BL CF CH CL CS EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR
|
| HN |
73; EPIPODOPHYLLOTOXIN was see under PODOPHYLLOTOXIN 1975
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| subClassOf | |
| Semantic type UMLS property | |
| Inverse of RB |
4375-07-9
L36H50F353
55568-79-1
477-47-4
0
4375-06-8
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| LT |
TRD
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| DC |
1
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| MDA |
19990101
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| type | |
| tui |
T109
T131
T121
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| cui |
C0524690
C0722658
C0730961
C0887023
C1135737
C0917757
C0887022
C0592268
C0700937
C0032334
C0086243
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| isa | |
| AN |
/biosyn permitted if by plant
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| Inverse of AQ |
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| OL |
use PODOPHYLLOTOXIN to search EPIPODOPHYLLOTOXIN 1975
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| TERMUI |
T032450
T616986
T032446
T032449
T032448
T616976
T616969
T360063
T616978
T360064
T360062
T359997
T032447
T616987
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