loading...| Preferred Name | Tissue Plasminogen Activator | |
| Synonyms |
Activase Plasminogen Activator, Tissue-Type Lysatec rt-PA Tissue Activator D-44 Lysatec rt PA Plasminogen Activator, Tissue Tisokinase Alteplase Lysatec rtPA T-Plasminogen Activator TTPA Tissue Type Plasminogen Activator Tissue Activator D 44 Plasminogen Activator, Tissue Type T Plasminogen Activator Actilyse Tissue-Type Plasminogen Activator |
|
| Definitions |
A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D010959 |
|
| altLabel |
Activase Plasminogen Activator, Tissue-Type Lysatec rt-PA Tissue Activator D-44 Lysatec rt PA Plasminogen Activator, Tissue Tisokinase Alteplase Lysatec rtPA T-Plasminogen Activator TTPA Tissue Type Plasminogen Activator Tissue Activator D 44 Plasminogen Activator, Tissue Type T Plasminogen Activator Actilyse Tissue-Type Plasminogen Activator |
|
| AQL |
AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
|
| cui |
C0032143 C0678113 C0701942 |
|
| DC |
1 |
|
| definition |
A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases. |
|
| DX |
19860101 |
|
| HN |
98(86) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
EC 3.4.21.68 0 |
|
| isa | ||
| LT |
TRD |
|
| Machine permutation |
98; see ALTEPLASE 1992-97; see PLASMINOGEN ACTIVATOR, TISSUE-TYPE 1986-91 |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C067262 http://purl.bioontology.org/ontology/MESH/C081981 http://purl.bioontology.org/ontology/MESH/C083865 http://purl.bioontology.org/ontology/MESH/C083866 http://purl.bioontology.org/ontology/MESH/C567341 http://purl.bioontology.org/ontology/MESH/C072781 http://purl.bioontology.org/ontology/MESH/C059835 http://purl.bioontology.org/ontology/MESH/C550736 http://purl.bioontology.org/ontology/MESH/C087896 http://purl.bioontology.org/ontology/MESH/C068645 http://purl.bioontology.org/ontology/MESH/C065621 http://purl.bioontology.org/ontology/MESH/C104096 http://purl.bioontology.org/ontology/MESH/C085027 http://purl.bioontology.org/ontology/MESH/C449559 http://purl.bioontology.org/ontology/MESH/C080391 http://purl.bioontology.org/ontology/MESH/C089949 http://purl.bioontology.org/ontology/MESH/C473928 |
|
| MDA |
19850612 |
|
| MMR |
20160701 |
|
| MN |
D08.811.277.656.959.350.875 D12.776.124.125.662.768 D23.119.970 D08.811.277.656.300.760.875 |
|
| notation |
D010959 |
|
| PA |
D005343 |
|
| prefLabel |
Tissue Plasminogen Activator |
|
| RR |
105857-23-6 (Alteplase) |
|
| TERMUI |
T707756 T032269 T032270 T032272 T365869 T032267 T032271 T032266 T505964 T032273 T032268 |
|
| TH |
US MX NLM (2009) UK NLM (2000) NL NLM (1999) CA JAN (19XX) ES NLM (1992) UNK (19XX) INN (19XX) DE AU NLM (1998) BAN (19XX) USAN (1989) IE |
|
| tui |
T116 T126 T121 |
|
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D012697 |