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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D010444
http://purl.bioontology.org/ontology/MESH/D010444
|
|---|---|
| Preferred Name | Peptide Elongation Factor Tu |
| Definitions |
A protein found in bacteria and eukaryotic mitochondria which delivers aminoacyl-tRNA's to the A site of the ribosome. The aminoacyl-tRNA is first bound to a complex of elongation factor Tu containing a molecule of bound GTP. The resulting complex is then bound to the 70S initiation complex. Simultaneously the GTP is hydrolyzed and a Tu-GDP complex is released from the 70S ribosome. The Tu-GTP complex is regenerated from the Tu-GDP complex by the Ts elongation factor and GTP.
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| Synonyms |
Protein Synthesis Elongation Factor Tu
Eucaryotic Elongation Factor Tu
Elongation Factor Tu
eEF-Tu
EF-Tu
EF Tu
Factor Tu, Elongation
eEF Tu
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A protein found in bacteria and eukaryotic mitochondria which delivers aminoacyl-tRNA's to the A site of the ribosome. The aminoacyl-tRNA is first bound to a complex of elongation factor Tu containing a molecule of bound GTP. The resulting complex is then bound to the 70S initiation complex. Simultaneously the GTP is hydrolyzed and a Tu-GDP complex is released from the 70S ribosome. The Tu-GTP complex is regenerated from the Tu-GDP complex by the Ts elongation factor and GTP. |
|---|---|
| altLabel |
Protein Synthesis Elongation Factor Tu
Eucaryotic Elongation Factor Tu
Elongation Factor Tu
eEF-Tu
EF-Tu
EF Tu
Factor Tu, Elongation
eEF Tu
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| prefLabel | Peptide Elongation Factor Tu
|
| Machine permutation | 86
|
| HN | 86
|
| Mapped from |
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| type | |
| tui |
T116
T126
T123
|
| TERMUI |
T030864
T030861
T788232
T030863
T030865
T030862
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| TH |
NLM (2012)
UNK (19XX)
NLM (1986)
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| MMR | 20210521
|
| notation | D010444
|
| Semantic type UMLS property | |
| Inverse of AQ |
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| DX | 19860101
|
| cui |
C0030933
C0013662
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| DC | 1
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| MN |
D12.776.476.338.100.700
D12.776.835.700.350.700
D12.776.157.325.150.700
D08.811.277.040.330.300.100.700
|
| AN | coordinate with MITOCHONDRIAL PROTEINS or BACTERIAL PROTEINS if pertinent
|
| AQL | AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
|
| Inverse of RB | EC 3.6.1.-
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| MDA | 19990101
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| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |