Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D010214
http://purl.bioontology.org/ontology/MESH/D010214
Preferred Name

Papillon-Lefevre Disease

Definitions
Rare, autosomal recessive disorder occurring between the first and fifth years of life. It is characterized by palmoplantar keratoderma with periodontitis followed by the premature shedding of both deciduous and permanent teeth. Mutations in the gene for CATHEPSIN C have been associated with this disease.
Synonyms
Papillon Lefevre Disease
Haim Monk Syndrome
Palmoplantar Periodontopathies, Keratosis
Papillon Lefevre Syndrome
Keratosis Palmoplantar Periodontopathies
Papillon-Lefevre Syndrome
Keratosis Palmoplantaris with Periodontopathia
Haim-Monk Syndrome
Keratosis Palmoplantar Periodontopathy
Type http://www.w3.org/2002/07/owl#Class
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