loading...| Preferred Name |
Nucleic Acid Denaturation |
|
| Synonyms |
Acid Denaturation, Nucleic Nucleic Acid Denaturations DNA Melting Denaturation, Nucleic Acid DNA Denaturation Denaturation, DNA Denaturation, RNA RNA Denaturation |
|
| Definitions |
Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D009691 |
|
| altLabel |
Acid Denaturation, Nucleic Nucleic Acid Denaturations DNA Melting Denaturation, Nucleic Acid DNA Denaturation Denaturation, DNA Denaturation, RNA RNA Denaturation |
|
| AN |
IM general only; coord NIM with DNA or RNA or specific (IM) |
|
| AQL |
DE GE PD RE |
|
| cui |
C1720789 C1720790 C0028600 |
|
| DC |
1 |
|
| definition |
Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible. |
|
| DX |
19700101 |
|
| FX |
D020871 |
|
| HN |
70(67) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000187 |
|
| Inverse of RO | ||
| Machine permutation |
70 |
|
| MDA |
19990101 |
|
| MMR |
20160617 |
|
| MN |
E05.393.640 G05.627 G02.111.603 |
|
| notation |
D009691 |
|
| prefLabel |
Nucleic Acid Denaturation |
|
| TERMUI |
T028819 T674637 T674636 T674638 |
|
| TH |
NLM (1967) NLM (2006) |
|
| tui |
T070 |
|
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D055614 |