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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D009627
http://purl.bioontology.org/ontology/MESH/D009627
|
|---|---|
| Preferred Name | Nomifensine |
| Definitions |
An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
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| Synonyms |
Hoe 984
Hoe-984
Hoe984
Nomifensin
Linamiphen
Nomifensine Maleate (1:1)
8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-
Merital
Nomifensine Maleate
Maleate, Nomifensine
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266) |
|---|---|
| altLabel |
Hoe 984
Hoe-984
Hoe984
Nomifensin
Linamiphen
Nomifensine Maleate (1:1)
8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-
Merital
Nomifensine Maleate
Maleate, Nomifensine
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|
| prefLabel | Nomifensine
|
| Machine permutation | 86; was see under ISOQUINOLINES 1978-85
|
| HN | 86(78); was see under ISOQUINOLINES 1978-85
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| Mapped from |
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| type | |
| isa | |
| PA | D018765
|
| tui |
T109
T121
|
| TERMUI |
T028632
T028637
T028636
T028634
T028635
T360163
T028633
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|
| TH |
NLM (1999)
FDA SRS (2014)
UNK (19XX)
INN (19XX)
USAN (1975)
BAN (19XX)
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|
| MMR | 20160531
|
| notation | D009627
|
| Semantic type UMLS property | |
| RR |
24526-64-5 (Nomifensine)
32795-47-4 (maleate (1:1))
76S8CUH5MR
|
| Inverse of AQ |
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|
| DX | 19860101
|
| cui |
C0028278
C0877847
C0028277
C0878159
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| DC | 1
|
| MN | D03.633.100.531.535
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| LT | TRD
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| AQL | AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
|
| Inverse of RB |
1LGS5JRP31
0
76S8CUH5MR
|
| MDA | 19990101
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |