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Medical Subject Headings
Last uploaded:
January 16, 2025
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Id | http://purl.bioontology.org/ontology/MESH/D009455
http://purl.bioontology.org/ontology/MESH/D009455
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Preferred Name | Neurofibroma |
Definitions |
A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)
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Synonyms |
Neurofibromas
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016) |
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altLabel |
Neurofibromas
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prefLabel |
Neurofibroma
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TH |
NLM (1966)
ORD (2010)
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notation |
D009455
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DX |
19660101
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MN |
C10.668.829.725.500.600
C10.551.775.500.750
C04.557.580.600.580
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MMR |
20090706
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AQL |
BL BS CF CH CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UL UR VE VI
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subClassOf | |
Semantic type UMLS property | |
DC |
1
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MDA |
19990101
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type | |
tui |
T191
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cui |
C0027830
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AN |
solitary; multiple = NEUROFIBROMATOSES but see MeSH definition; coord IM with precoord organ/neopl term (IM)
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Inverse of AQ |
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TERMUI |
T028172
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