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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D009455
http://purl.bioontology.org/ontology/MESH/D009455
|
|---|---|
| Preferred Name | Neurofibroma |
| Definitions |
A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)
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| Synonyms |
Neurofibromas
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016) |
|---|---|
| altLabel | Neurofibromas
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| prefLabel | Neurofibroma
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| type | |
| tui | T191
|
| TERMUI | T028172
|
| TH |
NLM (1966)
ORD (2010)
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| MMR | 20090706
|
| notation | D009455
|
| Semantic type UMLS property | |
| Inverse of AQ |
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| DX | 19660101
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| cui | C0027830
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| DC | 1
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| MN |
C10.668.829.725.500.600
C10.551.775.500.750
C04.557.580.600.580
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| AN | solitary; multiple = NEUROFIBROMATOSES but see MeSH definition; coord IM with precoord organ/neopl term (IM)
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| AQL | BL BS CF CH CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UL UR VE VI
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| MDA | 19990101
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| subClassOf |
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| No notes to display |