Medical Subject Headings

Last uploaded: August 28, 2024

Preferred Name	Keratins
Synonyms	Keratin Keratin Associated Protein Keratin Associated Proteins Associated Protein, Keratin alpha Keratin Keratin-Associated Proteins alpha-Keratin Cytokeratin Protein, Keratin Associated
Definitions	A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
ID	http://purl.bioontology.org/ontology/MESH/D007633
altLabel	Keratin Keratin Associated Protein Keratin Associated Proteins Associated Protein, Keratin alpha Keratin Keratin-Associated Proteins alpha-Keratin Cytokeratin Protein, Keratin Associated
AQL	AD AE AG AI AN BI BL CF CH CL CS DE EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui	C1621904 C0010803 C0522084
DC	1
definition	A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
DX	20070101
FX	D007382 D015603
HN	2007(1966)
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	68238-35-7 0
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D019396 http://purl.bioontology.org/ontology/MESH/D015603 http://purl.bioontology.org/ontology/MESH/D007382
Machine permutation	2007; see KERATIN 1966-2006; KERATIN-ASSOCIATED PROTEINS was indexed under KERATIN 2000-2006, & under PROTEINS 1993-1999
Mapped from	http://purl.bioontology.org/ontology/MESH/C001500 http://purl.bioontology.org/ontology/MESH/C000707752 http://purl.bioontology.org/ontology/MESH/C084341 http://purl.bioontology.org/ontology/MESH/C586304 http://purl.bioontology.org/ontology/MESH/C586305 http://purl.bioontology.org/ontology/MESH/C475001 http://purl.bioontology.org/ontology/MESH/C400901 http://purl.bioontology.org/ontology/MESH/C118917 http://purl.bioontology.org/ontology/MESH/C587433 http://purl.bioontology.org/ontology/MESH/C097184 http://purl.bioontology.org/ontology/MESH/C004818 http://purl.bioontology.org/ontology/MESH/C544964 http://purl.bioontology.org/ontology/MESH/C544963 http://purl.bioontology.org/ontology/MESH/C028515 http://purl.bioontology.org/ontology/MESH/C513551 http://purl.bioontology.org/ontology/MESH/C090852 http://purl.bioontology.org/ontology/MESH/C000656764 http://purl.bioontology.org/ontology/MESH/C068639 http://purl.bioontology.org/ontology/MESH/C417962 http://purl.bioontology.org/ontology/MESH/C417963 http://purl.bioontology.org/ontology/MESH/C477829 http://purl.bioontology.org/ontology/MESH/C489973 http://purl.bioontology.org/ontology/MESH/C121278 http://purl.bioontology.org/ontology/MESH/C501290 http://purl.bioontology.org/ontology/MESH/C521341 http://purl.bioontology.org/ontology/MESH/C526516 http://purl.bioontology.org/ontology/MESH/C002552 http://purl.bioontology.org/ontology/MESH/C114908 http://purl.bioontology.org/ontology/MESH/C585494 http://purl.bioontology.org/ontology/MESH/C000656765
MDA	19990101
MMR	20220407
MN	D05.750.078.593.450 D12.776.220.475.450 D12.776.860.607
notation	D007633
prefLabel	Keratins
RR	9008-18-8 (other number)
TERMUI	T022937 T000998864 T022922 T664998 T665143 T665513
TH	NLM (1966) UNK (19XX) NLM (2021) NLM (2007)
tui	T116 T123
subClassOf	http://purl.bioontology.org/ontology/MESH/D012596 http://purl.bioontology.org/ontology/MESH/D007381

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/MSHFRE/D007633	MSHFRE	CUI
http://purl.bioontology.org/ontology/RCD/X80h2	RCD	CUI
http://purl.bioontology.org/ontology/MSHFRE/D007633	MSHFRE	CUI
http://purl.bioontology.org/ontology/CSP/2447-0900	CRISP	CUI
http://purl.bioontology.org/ontology/MSHFRE/D007633	MSHFRE	CUI
http://purl.bioontology.org/ontology/LNC/LP14679-2	LOINC	CUI
http://purl.bioontology.org/ontology/LNC/LP18175-7	LOINC	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/259987000	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000169473	NDFRT	CUI
http://purl.bioontology.org/ontology/SCTSPA/259987000	SCTSPA	CUI
http://purl.bioontology.org/ontology/SCTSPA/102666002	SCTSPA	CUI
http://purl.bioontology.org/ontology/SNMI/F-620E0	SNMI	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/102666002	SNOMEDCT	CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.860.607	RH-MESH	LOOM
http://localhost/plosthes.2017-1#5140	PLOSTHES	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.220.475.450	RH-MESH	LOOM
http://purl.obolibrary.org/obo/MESH_D007633	BERO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018817	PMAPP-PMO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D007633	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D05.750.078.593.450	RH-MESH	LOOM
http://purl.obolibrary.org/obo/OMIT_0008742	OMIT	LOOM