Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D007633
http://purl.bioontology.org/ontology/MESH/D007633
Preferred Name

Keratins

Definitions
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
Synonyms
Keratin
Keratin Associated Protein
Keratin Associated Proteins
Associated Protein, Keratin
alpha Keratin
Keratin-Associated Proteins
alpha-Keratin
Cytokeratin
Protein, Keratin Associated
Type http://www.w3.org/2002/07/owl#Class
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