The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
ID
http://purl.bioontology.org/ontology/MESH/D007371
altLabel
Interferon, gamma
Immune Interferon
Interferon, Type II
gamma-Interferon
Interferon, Immune
Interferon Type II
Interferon gamma (human lymphocyte protein moiety reduced)
Type II Interferon
AQL
AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui
C3539881
DC
1
definition
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
DX
19830101
FX
D059425
HN
2009(1983); INTERFERON-GAMMA was INTERFERON, GAMMA 1983-1990