Medical Subject Headings

Last uploaded: August 28, 2024
Preferred Name

Immunoglobulin Fab Fragments
Synonyms

Fab Fragment

Immunoglobulin Fragments, Fab

Fragment Immunoglobulins, Fab

Fab Fragment Immunoglobulins

Immunoglobulins, Fab

Fragment, Fab

Immunoglobulin Fab Fragment

Fab Fragments, Immunoglobulin

Immunoglobulins, Fab Fragment

Fab Fragment, Immunoglobulin

Fab Fragments

Fab Immunoglobulin Fragments

Ig Fab Fragments

Definitions

Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.

ID

http://purl.bioontology.org/ontology/MESH/D007140

altLabel

Fab Fragment

Immunoglobulin Fragments, Fab

Fragment Immunoglobulins, Fab

Fab Fragment Immunoglobulins

Immunoglobulins, Fab

Fragment, Fab

Immunoglobulin Fab Fragment

Fab Fragments, Immunoglobulin

Immunoglobulins, Fab Fragment

Fab Fragment, Immunoglobulin

Fab Fragments

Fab Immunoglobulin Fragments

Ig Fab Fragments

AQL

AD AE AN BI BL CF CH CL DE EC GE HI IM IP ME PD PH PO RE TO TU UL UR

cui

C0021031

DC

1

definition

Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.

DX

19730101

HN

2006 (1973)

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000096

http://purl.bioontology.org/ontology/MESH/Q000627

http://purl.bioontology.org/ontology/MESH/Q000648

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000502

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000187

http://purl.bioontology.org/ontology/MESH/Q000235

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000528

Inverse of RB

0

isa

http://purl.bioontology.org/ontology/MESH/D007155

Machine permutation

2006; was IMMUNOGLOBULINS, FAB 1973-2005

Mapped from

http://purl.bioontology.org/ontology/MESH/C465643

http://purl.bioontology.org/ontology/MESH/C587873

http://purl.bioontology.org/ontology/MESH/C079556

http://purl.bioontology.org/ontology/MESH/C079557

http://purl.bioontology.org/ontology/MESH/C105869

http://purl.bioontology.org/ontology/MESH/C041323

http://purl.bioontology.org/ontology/MESH/C000613977

http://purl.bioontology.org/ontology/MESH/C527478

http://purl.bioontology.org/ontology/MESH/C000607972

http://purl.bioontology.org/ontology/MESH/C109536

http://purl.bioontology.org/ontology/MESH/C061184

http://purl.bioontology.org/ontology/MESH/C431183

http://purl.bioontology.org/ontology/MESH/C477844

http://purl.bioontology.org/ontology/MESH/C000603963

http://purl.bioontology.org/ontology/MESH/C107416

http://purl.bioontology.org/ontology/MESH/C000606142

http://purl.bioontology.org/ontology/MESH/C513813

http://purl.bioontology.org/ontology/MESH/C000595441

http://purl.bioontology.org/ontology/MESH/C050199

http://purl.bioontology.org/ontology/MESH/C117771

http://purl.bioontology.org/ontology/MESH/C067357

http://purl.bioontology.org/ontology/MESH/C522802

MDA

19990101

MMR

20200527

MN

D12.644.541.500.650

D12.776.377.715.548.680.650

D12.776.124.486.485.680.650

D12.776.124.790.651.680.650

notation

D007140

PA

D007155

prefLabel

Immunoglobulin Fab Fragments

TERMUI

T001081132

T634137

T000962317

T021383

T633956

T634138

T021382

T633959

TH

NLM (1973)

NLM (2020)

NLM (1992)

NLM (2021)

NLM (2006)

tui

T116

T129

subClassOf

http://purl.bioontology.org/ontology/MESH/D007128

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