Medical Subject Headings

Last uploaded: August 28, 2024
Preferred Name

Hydroxymethylglutaryl-CoA Synthase
Synonyms

Synthase, Hydroxymethylglutaryl-CoA

synthase, HMG-CoA

HMG CoA Synthase

Hydroxymethylglutaryl CoA Synthase

3 hydroxy 3 methylglutaryl coenzyme A synthase

A synthase, 3-hydroxy-3-methylglutaryl-coenzyme

CoA Synthase, HMG

synthase, 3-hydroxy-3-methylglutaryl-coenzyme A

3-hydroxy-3-methylglutaryl-coenzyme A synthase

(S)-3-Hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)

Synthase, HMG CoA

HMG-CoA synthase

Definitions

An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis. This enzyme was formerly listed as EC 4.1.3.5.

ID

http://purl.bioontology.org/ontology/MESH/D006904

altLabel

Synthase, Hydroxymethylglutaryl-CoA

synthase, HMG-CoA

HMG CoA Synthase

Hydroxymethylglutaryl CoA Synthase

3 hydroxy 3 methylglutaryl coenzyme A synthase

A synthase, 3-hydroxy-3-methylglutaryl-coenzyme

CoA Synthase, HMG

synthase, 3-hydroxy-3-methylglutaryl-coenzyme A

3-hydroxy-3-methylglutaryl-coenzyme A synthase

(S)-3-Hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)

Synthase, HMG CoA

HMG-CoA synthase

AQL

AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR

cui

C0020375

DC

1

definition

An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis. This enzyme was formerly listed as EC 4.1.3.5.

DX

19910101

HN

1991(1975);

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000096

http://purl.bioontology.org/ontology/MESH/Q000172

http://purl.bioontology.org/ontology/MESH/Q000627

http://purl.bioontology.org/ontology/MESH/Q000648

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000502

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000187

http://purl.bioontology.org/ontology/MESH/Q000235

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000528

Inverse of RB

EC 2.3.3.10

Machine permutation

1991; HMG-COA SYNTHASE was indexed under HYDROXYMETHYLGLUTARYL-COA SYNTHASE 2005-2008, & under COENZYME A LIGASES 2001-2005

Mapped from

http://purl.bioontology.org/ontology/MESH/C000607500

http://purl.bioontology.org/ontology/MESH/C000599408

http://purl.bioontology.org/ontology/MESH/C000621002

http://purl.bioontology.org/ontology/MESH/C567784

MDA

19741119

MMR

20190429

MN

D08.811.913.050.612

notation

D006904

prefLabel

Hydroxymethylglutaryl-CoA Synthase

RR

9027-44-5 (CAS RN)

TERMUI

T000952289

T463133

T020786

T463132

TH

NLM (2009)

NLM (2020)

NLM (1975)

tui

T116

T126

subClassOf

http://purl.bioontology.org/ontology/MESH/D000217

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