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Medical Subject Headings
Preferred Name | Hydroxymethylglutaryl-CoA Synthase | |
Synonyms |
Synthase, Hydroxymethylglutaryl-CoA synthase, HMG-CoA HMG CoA Synthase Hydroxymethylglutaryl CoA Synthase 3 hydroxy 3 methylglutaryl coenzyme A synthase A synthase, 3-hydroxy-3-methylglutaryl-coenzyme CoA Synthase, HMG synthase, 3-hydroxy-3-methylglutaryl-coenzyme A 3-hydroxy-3-methylglutaryl-coenzyme A synthase (S)-3-Hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating) Synthase, HMG CoA HMG-CoA synthase |
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Definitions |
An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis. This enzyme was formerly listed as EC 4.1.3.5. |
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ID |
http://purl.bioontology.org/ontology/MESH/D006904 |
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altLabel |
Synthase, Hydroxymethylglutaryl-CoA synthase, HMG-CoA HMG CoA Synthase Hydroxymethylglutaryl CoA Synthase 3 hydroxy 3 methylglutaryl coenzyme A synthase A synthase, 3-hydroxy-3-methylglutaryl-coenzyme CoA Synthase, HMG synthase, 3-hydroxy-3-methylglutaryl-coenzyme A 3-hydroxy-3-methylglutaryl-coenzyme A synthase (S)-3-Hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating) Synthase, HMG CoA HMG-CoA synthase
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AQL |
AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
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cui |
C0020375
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DC |
1
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definition |
An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis. This enzyme was formerly listed as EC 4.1.3.5.
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DX |
19910101
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HN |
1991(1975);
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Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
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Inverse of RB |
EC 2.3.3.10
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Machine permutation |
1991; HMG-COA SYNTHASE was indexed under HYDROXYMETHYLGLUTARYL-COA SYNTHASE 2005-2008, & under COENZYME A LIGASES 2001-2005
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Mapped from |
http://purl.bioontology.org/ontology/MESH/C000607500 http://purl.bioontology.org/ontology/MESH/C000599408 |
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MDA |
19741119
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MMR |
20190429
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MN |
D08.811.913.050.612
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notation |
D006904
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prefLabel |
Hydroxymethylglutaryl-CoA Synthase
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RR |
9027-44-5 (CAS RN)
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TERMUI |
T000952289 T463133 T020786 T463132
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TH |
NLM (2009) NLM (2020) NLM (1975)
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tui |
T116 T126
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subClassOf |
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