Medical Subject Headings

Last uploaded: January 31, 2024

Details
Visualization
Notes ( 0 )
Class Mappings ( )

Preferred Name	Histone Deacetylases
Synonyms	Deacetylases, Histone Class II Histone Deacetylases Complexes, Histone Deacetylase Deacetylase Complexes, Histone Class I Histone Deacetylases Histone Deacetylase Complexes Deacetylase, Histone HDAC Proteins Histone Deacetylase
Definitions	Deacetylases that remove N-acetyl groups from amino side chains of the amino acids of HISTONES. The enzyme family can be divided into at least three structurally-defined subclasses. Class I and class II deacetylases utilize a zinc-dependent mechanism. The sirtuin histone deacetylases belong to class III and are NAD-dependent enzymes.
ID	http://purl.bioontology.org/ontology/MESH/D006655
altLabel	Deacetylases, Histone Class II Histone Deacetylases Complexes, Histone Deacetylase Deacetylase Complexes, Histone Class I Histone Deacetylases Histone Deacetylase Complexes Deacetylase, Histone HDAC Proteins Histone Deacetylase
AQL	AD AE AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui	C1167142 C2718090 C0019643 C2718089
DC	1
definition	Deacetylases that remove N-acetyl groups from amino side chains of the amino acids of HISTONES. The enzyme family can be divided into at least three structurally-defined subclasses. Class I and class II deacetylases utilize a zinc-dependent mechanism. The sirtuin histone deacetylases belong to class III and are NAD-dependent enzymes.
DX	19910101
EC	antagonists & inhibitors:Histone Deacetylase Inhibitors
HN	2003; use AMIDOHYDROLASES 1975-1990
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	EC 3.5.1.98 0
Machine permutation	2003; see HISTONE DEACETYLASE 1991-2002; see AMIDOHYDROLASES 1975-1990
Mapped from	http://purl.bioontology.org/ontology/MESH/C122050 http://purl.bioontology.org/ontology/MESH/C071665 http://purl.bioontology.org/ontology/MESH/C479923 http://purl.bioontology.org/ontology/MESH/C072617 http://purl.bioontology.org/ontology/MESH/C519410 http://purl.bioontology.org/ontology/MESH/C507989 http://purl.bioontology.org/ontology/MESH/C499673 http://purl.bioontology.org/ontology/MESH/C582193 http://purl.bioontology.org/ontology/MESH/C576359 http://purl.bioontology.org/ontology/MESH/C498619 http://purl.bioontology.org/ontology/MESH/C498618 http://purl.bioontology.org/ontology/MESH/C561595 http://purl.bioontology.org/ontology/MESH/C489689 http://purl.bioontology.org/ontology/MESH/C510447 http://purl.bioontology.org/ontology/MESH/C447828 http://purl.bioontology.org/ontology/MESH/C000624256 http://purl.bioontology.org/ontology/MESH/C000590683 http://purl.bioontology.org/ontology/MESH/C543274 http://purl.bioontology.org/ontology/MESH/C543273 http://purl.bioontology.org/ontology/MESH/C000619240 http://purl.bioontology.org/ontology/MESH/C400300 http://purl.bioontology.org/ontology/MESH/C114411 http://purl.bioontology.org/ontology/MESH/C000722630 http://purl.bioontology.org/ontology/MESH/C509118 http://purl.bioontology.org/ontology/MESH/C556904 http://purl.bioontology.org/ontology/MESH/C492634 http://purl.bioontology.org/ontology/MESH/C492635 http://purl.bioontology.org/ontology/MESH/C447899 http://purl.bioontology.org/ontology/MESH/C000708107 http://purl.bioontology.org/ontology/MESH/C491870 http://purl.bioontology.org/ontology/MESH/C518292 http://purl.bioontology.org/ontology/MESH/C000598222 http://purl.bioontology.org/ontology/MESH/C113294 http://purl.bioontology.org/ontology/MESH/C530050 http://purl.bioontology.org/ontology/MESH/C486545 http://purl.bioontology.org/ontology/MESH/C486544 http://purl.bioontology.org/ontology/MESH/C000630397 http://purl.bioontology.org/ontology/MESH/C583167 http://purl.bioontology.org/ontology/MESH/C000628115 http://purl.bioontology.org/ontology/MESH/C484391 http://purl.bioontology.org/ontology/MESH/C000726117 http://purl.bioontology.org/ontology/MESH/C512518 http://purl.bioontology.org/ontology/MESH/C512517 http://purl.bioontology.org/ontology/MESH/C000610747 http://purl.bioontology.org/ontology/MESH/C438596 http://purl.bioontology.org/ontology/MESH/C573088 http://purl.bioontology.org/ontology/MESH/C559944 http://purl.bioontology.org/ontology/MESH/C077490 http://purl.bioontology.org/ontology/MESH/C462506 http://purl.bioontology.org/ontology/MESH/C000629583 http://purl.bioontology.org/ontology/MESH/C404500 http://purl.bioontology.org/ontology/MESH/C507152 http://purl.bioontology.org/ontology/MESH/C528111 http://purl.bioontology.org/ontology/MESH/C491869 http://purl.bioontology.org/ontology/MESH/C000625964 http://purl.bioontology.org/ontology/MESH/C489690 http://purl.bioontology.org/ontology/MESH/C561201 http://purl.bioontology.org/ontology/MESH/C552726 http://purl.bioontology.org/ontology/MESH/C409470 http://purl.bioontology.org/ontology/MESH/C000603105 http://purl.bioontology.org/ontology/MESH/C508305 http://purl.bioontology.org/ontology/MESH/C521258 http://purl.bioontology.org/ontology/MESH/C521257 http://purl.bioontology.org/ontology/MESH/C511735 http://purl.bioontology.org/ontology/MESH/C583975 http://purl.bioontology.org/ontology/MESH/C071731 http://purl.bioontology.org/ontology/MESH/C430718 http://purl.bioontology.org/ontology/MESH/C559672 http://purl.bioontology.org/ontology/MESH/C000606948 http://purl.bioontology.org/ontology/MESH/C120917 http://purl.bioontology.org/ontology/MESH/C432452
MDA	19741119
MMR	20090706
MN	D08.811.277.087.520
notation	D006655
prefLabel	Histone Deacetylases
RR	EC 3.5.1.98
TERMUI	T733159 T485905 T483423 T731945 T020050 T731944
TH	NLM (1975) NLM (2003) NLM (2010)
tui	T116 T026 T126
subClassOf	http://purl.bioontology.org/ontology/MESH/D000581

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display

Create mapping

Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/MSHFRE/D006655	MSHFRE	CUI
http://purl.bioontology.org/ontology/MSHFRE/D006655	MSHFRE	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000167679	NDFRT	CUI
http://purl.bioontology.org/ontology/MSHFRE/D006655	MSHFRE	CUI
http://purl.bioontology.org/ontology/CSP/0116-0420	CRISP	CUI
http://purl.bioontology.org/ontology/MSHFRE/D006655	MSHFRE	CUI
http://www.phoc.org.cn/pmo/class/PMO_00019304	PMAPP-PMO	LOOM
http://purl.obolibrary.org/obo/OMIT_0007812	OMIT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D006655	RH-MESH	LOOM
http://purl.jp/bio/4/id/200906032003454679	IOBC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D08.811.277.087.520	RH-MESH	LOOM
http://purl.obolibrary.org/obo/MESH_D006655	BERO	LOOM