Medical Subject Headings

Last uploaded: January 16, 2025

Id	http://purl.bioontology.org/ontology/MESH/D006646 http://purl.bioontology.org/ontology/MESH/D006646
Preferred Name	Histiocytosis, Langerhans-Cell
Definitions	A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.
Synonyms	Syndrome, Hand-Schüller-Christian Histiocytosis X Letterer-Siwe Disease Pulmonary Histiocytosis X Histiocytosis, Type 2 Disease, Hand-Schüller-Christian Cell Histiocytoses, Langerhans Pulmonary Langerhans Cell Granulomatosis Histiocytosis-X Syndrome, Hand-Schueller-Christian Letterer Siwe Disease Non-Lipid Reticuloendothelioses Hand-Schüller-Christian Syndrome Cell Granulomatoses, Langerhans Granulomatosis, Langerhans-Cell Histiocytosis, Generalized Disease, Hand-Schueller-Christian Generalized Histiocytosis Histiocytoses, Generalized Histiocytosis, Langerhans Cell Type 2 Histiocytosis Hashimoto-Pritzger Disease Hand-Schueller-Christian Syndrome Non-Lipid Reticuloendotheliosis Reticuloendothelioses, Non-Lipid Hashimoto Pritzger Disease Granulomatoses, Langerhans Cell Disease, Hashimoto-Pritzger Reticuloendotheliosis, Systemic Aleukemic Cell Histiocytosis, Langerhans Cell Granulomatosis, Langerhans Histiocytosis X, Pulmonary Generalized Histiocytoses Histiocytoses, Type 2 Hand-Schüller-Christian Disease Hand-Schueller-Christian Disease Langerhans Cell Histiocytoses Langerhans Cell Histiocytosis Type 2 Histiocytoses Hand Schueller Christian Syndrome Systemic Aleukemic Reticuloendotheliosis Langerhans-Cell Histiocytosis Granulomatosis, Langerhans Cell Diseases, Hashimoto-Pritzger Langerhans-Cell Granulomatosis Schueller Christian Disease Disease, Schueller-Christian Reticuloendotheliosis, Non-Lipid Systemic Aleukemic Reticuloendothelioses Reticuloendothelioses, Systemic Aleukemic Aleukemic Reticuloendotheliosis, Systemic Langerhans Cell Granulomatosis Schueller-Christian Disease Non Lipid Reticuloendotheliosis Langerhans Cell Granulomatosis, Pulmonary Hashimoto-Pritzger Diseases Aleukemic Reticuloendothelioses, Systemic Hand Schüller Christian Syndrome Langerhans Cell Granulomatoses Histiocytoses, Langerhans Cell Hand Schueller Christian Disease Disease, Letterer-Siwe Hand Schüller Christian Disease See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.
altLabel	Syndrome, Hand-Schüller-Christian Histiocytosis X Letterer-Siwe Disease Pulmonary Histiocytosis X Histiocytosis, Type 2 Disease, Hand-Schüller-Christian Cell Histiocytoses, Langerhans Pulmonary Langerhans Cell Granulomatosis Histiocytosis-X Syndrome, Hand-Schueller-Christian Letterer Siwe Disease Non-Lipid Reticuloendothelioses Hand-Schüller-Christian Syndrome Cell Granulomatoses, Langerhans Granulomatosis, Langerhans-Cell Histiocytosis, Generalized Disease, Hand-Schueller-Christian Generalized Histiocytosis Histiocytoses, Generalized Histiocytosis, Langerhans Cell Type 2 Histiocytosis Hashimoto-Pritzger Disease Hand-Schueller-Christian Syndrome Non-Lipid Reticuloendotheliosis Reticuloendothelioses, Non-Lipid Hashimoto Pritzger Disease Granulomatoses, Langerhans Cell Disease, Hashimoto-Pritzger Reticuloendotheliosis, Systemic Aleukemic Cell Histiocytosis, Langerhans Cell Granulomatosis, Langerhans Histiocytosis X, Pulmonary Generalized Histiocytoses Histiocytoses, Type 2 Hand-Schüller-Christian Disease Hand-Schueller-Christian Disease Langerhans Cell Histiocytoses Langerhans Cell Histiocytosis Type 2 Histiocytoses Hand Schueller Christian Syndrome Systemic Aleukemic Reticuloendotheliosis Langerhans-Cell Histiocytosis Granulomatosis, Langerhans Cell Diseases, Hashimoto-Pritzger Langerhans-Cell Granulomatosis Schueller Christian Disease Disease, Schueller-Christian Reticuloendotheliosis, Non-Lipid Systemic Aleukemic Reticuloendothelioses Reticuloendothelioses, Systemic Aleukemic Aleukemic Reticuloendotheliosis, Systemic Langerhans Cell Granulomatosis Schueller-Christian Disease Non Lipid Reticuloendotheliosis Langerhans Cell Granulomatosis, Pulmonary Hashimoto-Pritzger Diseases Aleukemic Reticuloendothelioses, Systemic Hand Schüller Christian Syndrome Langerhans Cell Granulomatoses Histiocytoses, Langerhans Cell Hand Schueller Christian Disease Disease, Letterer-Siwe Hand Schüller Christian Disease See more See less
prefLabel	Histiocytosis, Langerhans-Cell
TH	OMIM (2013) NLM (2009) NLM (1966) NLM (1990) NLM (1976) NLM (2012) UNK (19XX) GHR (2014) NLM (2011) ORD (2010) See more See less
notation	D006646
DX	19760101
Machine permutation	90; was see under RETICULOENDOTHELIOSIS 1965-75; was HISTIOCYTOSIS X 1975-89
MN	C15.604.250.400 C08.381.483.375
MMR	20230531
Mapped from	http://purl.bioontology.org/ontology/MESH/C535843 http://purl.bioontology.org/ontology/MESH/C538636
AQL	BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI
HN	90(75); was see under RETICULOENDOTHELIOSIS 1966-75; was HISTIOCYTOSIS X 1975-89
subClassOf	http://purl.bioontology.org/ontology/MESH/D015614 http://purl.bioontology.org/ontology/MESH/D017563
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T047 http://purl.bioontology.org/ontology/STY/T191
DC	1
MDA	19750725
type	http://www.w3.org/2002/07/owl#Class
tui	T047 T191
cui	C5574737 C3661439 C0023381 C0019621 C1455705
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000178 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000469 http://purl.bioontology.org/ontology/MESH/Q000151 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000209 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000523 http://purl.bioontology.org/ontology/MESH/Q000401 See more See less
OL	use HISTIOCYTOSIS, LANGERHANS-CELL to search HISTIOCYTOSIS X 1975-89; use RETICULOENDOTHELIOSIS 1966-74
TERMUI	T703224 T023616 T020011 T768825 T782968 T020013 T768737 T782967 T705960 T782969 T841870 T018895 T023615 T018896 T811619 T703203 T703225 T020012 T841871 T768826 T020014 See more See less

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display