Medical Subject Headings

Last uploaded: January 16, 2025
Id http://purl.bioontology.org/ontology/MESH/D006080
http://purl.bioontology.org/ontology/MESH/D006080
Preferred Name

Ovarian Follicle

Definitions
The blister-like mature ovarian follicle containing the OVUM surrounded by an accumulation of GRANULOSA CELLS (the cumulus oophorus) and an increasing volume of FOLLICULAR FLUID. The mature Graafian follicle is ready to release the ovum by the process of OVULATION. An OOCYTE-containing structure in the cortex of the OVARY. The oocyte is enclosed by a layer of GRANULOSA CELLS providing a nourishing microenvironment (FOLLICULAR FLUID). The number and size of follicles vary depending on the age and reproductive state of the female. The growing follicles are divided into five stages: primary, secondary, tertiary, Graafian, and atretic. Follicular growth and steroidogenesis depend on the presence of GONADOTROPINS. A degenerating ovarian follicle as a result of atresia (FOLLICULAR ATRESIA). During atresia, the OOCYTE and GRANULOSA CELLS within the basal lamina die and are replaced by fibrous tissue.
Synonyms
Follicles, Atretic
Follicle, Atretic
Atretic Follicles
Follicle, Graafian
Atretic Follicle
Graafian Follicles
Graafian Follicle
Follicles, Graafian
Follicles, Ovarian
Follicle, Ovarian
Ovarian Follicles
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Type http://www.w3.org/2002/07/owl#Class
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