Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens. The accumulation of globoside in tissue, due to a defect in hexosaminidases A and B, is the cause of Sandhoff disease.
ID
http://purl.bioontology.org/ontology/MESH/D005915
altLabel
Lacto N tetraosylceramide
Lacto-N-tetraosylceramide
Lactoneotetraosylceramide
Lacto-N-neotetraosylceramide
Lacto N neotetraosylceramide
Cytolipins
AN
/biosyn /physiol permitted
AQL
AD AE AG AI AN BI BL CF CH CL CS DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR
cui
C0086092
C0017647
DC
1
definition
Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens. The accumulation of globoside in tissue, due to a defect in hexosaminidases A and B, is the cause of Sandhoff disease.