Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D005600
http://purl.bioontology.org/ontology/MESH/D005600
Preferred Name

Fragile X Syndrome

Definitions
A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
Synonyms
Syndromes, Fragile X
Syndrome, FRAXE
Marker X Syndrome
Syndromes, FRAXA
Fragile X Mental Retardation Syndrome
X Linked Mental Retardation and Macroorchidism
FRAXA Syndromes
Martin Bell Syndrome
Syndromes, Marker X
Marker X Syndromes
Mar (X) Syndrome
X-Linked Mental Retardation and Macroorchidism
FRAXE Syndrome
Syndrome, FRAXA
Syndrome, Marker X
Syndromes, FRAXE
Fragile X Syndromes
FRAXE Syndromes
FRAXA Syndrome
Mental Retardation, X-Linked, Associated With Fragile Site Fraxe
Syndrome, Fragile X
Fragile X-F Mental Retardation Syndrome
Mental Retardation, X-Linked, Associated With Marxq28
Martin-Bell Syndrome
Fra(X) Syndrome
Syndrome, Martin-Bell
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