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Medical Subject Headings
| Preferred Name | Ferrochelatase | |
| Synonyms |
Ferro-Lyase, Protoheme Chelatase, Porphyrin-Metal Zinc Chelatase Synthetase, Heme Chelatase, Zinc Heme Synthetase Protoheme ferro-lyase Protoheme Ferro Lyase Porphyrin Metal Chelatase Protoheme Ferro-Lyase Porphyrin-Metal Chelatase |
|
| Definitions |
A mitochondrial enzyme found in a wide variety of cells and tissues. It is the final enzyme in the 8-enzyme biosynthetic pathway of HEME. Ferrochelatase catalyzes ferrous insertion into protoporphyrin IX to form protoheme or heme. Deficiency in this enzyme results in ERYTHROPOIETIC PROTOPORPHYRIA. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D005294 |
|
| altLabel |
Ferro-Lyase, Protoheme Chelatase, Porphyrin-Metal Zinc Chelatase Synthetase, Heme Chelatase, Zinc Heme Synthetase Protoheme ferro-lyase Protoheme Ferro Lyase Porphyrin Metal Chelatase Protoheme Ferro-Lyase Porphyrin-Metal Chelatase
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|
| AQL |
AD AE AI AN BI BL CF CH CL CS DE EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
|
|
| cui |
C0043484 C0015880
|
|
| DC |
1
|
|
| definition |
A mitochondrial enzyme found in a wide variety of cells and tissues. It is the final enzyme in the 8-enzyme biosynthetic pathway of HEME. Ferrochelatase catalyzes ferrous insertion into protoporphyrin IX to form protoheme or heme. Deficiency in this enzyme results in ERYTHROPOIETIC PROTOPORPHYRIA.
|
|
| DX |
19910101
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|
| EC |
deficiency:Protoporphyria, Erythropoietic
|
|
| HN |
1991(1977); use LYASES 1977-1990
|
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
EC 4.99.1.1
|
|
| Inverse of RO | ||
| Machine permutation |
1991; see LYASES 1977-1990
|
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C103747 http://purl.bioontology.org/ontology/MESH/C000706763 |
|
| MDA |
19760427
|
|
| MMR |
20110624
|
|
| MN |
D08.811.520.500 D12.776.157.427.374.375.957 D12.776.575.562 D12.776.556.579.374.375.617
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|
| notation |
D005294
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|
| prefLabel |
Ferrochelatase
|
|
| RR |
9012-93-5 (CAS RN) EC 4.99.1.1
|
|
| TERMUI |
T016184 T016185 T016182 T016186 T016183
|
|
| TH |
NLM (1977) NLM (1990) UNK (19XX)
|
|
| tui |
T116 T126
|
|
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D007506 |
| Delete | Subject | Author | Type | Created |
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