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Last uploaded: January 31, 2024

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Preferred Name	DNA-Directed DNA Polymerase
Synonyms	DNA Polymerase DNA Polymerase N3 Polymerase, DNA DNA Polymerases, DNA-Dependent Polymerase, DNA-Directed DNA Polymerase N3, DNA Polymerases, DNA DNA Dependent DNA Polymerases Polymerases, DNA-Dependent DNA DNA-Dependent DNA Polymerases Deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) DNA Polymerase, DNA-Directed DNA Directed DNA Polymerase DNA Polymerases
Definitions	DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair.
ID	http://purl.bioontology.org/ontology/MESH/D004259
altLabel	DNA Polymerase DNA Polymerase N3 Polymerase, DNA DNA Polymerases, DNA-Dependent Polymerase, DNA-Directed DNA Polymerase N3, DNA Polymerases, DNA DNA Dependent DNA Polymerases Polymerases, DNA-Dependent DNA DNA-Dependent DNA Polymerases Deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) DNA Polymerase, DNA-Directed DNA Directed DNA Polymerase DNA Polymerases
AN	general; prefer specifics
AQL	AD AE AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui	C0012891 C0012892
DC	1
definition	DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair.
DX	19770101
EC	antagonists & inhibitors:Nucleic Acid Synthesis Inhibitors
HN	98(68); for DNA POLYMERASE use DNA NUCLEOTIDYLTRANSFERASES 1968-76
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	EC 2.7.7.7 0
Machine permutation	98; see DNA POLYMERASES 1977-97, for DNA POLYMERASE see DNA NUCLEOTIDYLTRANSFERASES 1973-76, see DNA NUCLEOTIDYLTRANSFERASE 1968-72
Mapped from	http://purl.bioontology.org/ontology/MESH/C109367 http://purl.bioontology.org/ontology/MESH/C432942 http://purl.bioontology.org/ontology/MESH/C432943 http://purl.bioontology.org/ontology/MESH/C088944 http://purl.bioontology.org/ontology/MESH/C088943 http://purl.bioontology.org/ontology/MESH/C084163 http://purl.bioontology.org/ontology/MESH/C585901 http://purl.bioontology.org/ontology/MESH/C498614 http://purl.bioontology.org/ontology/MESH/C498615 http://purl.bioontology.org/ontology/MESH/C498613 http://purl.bioontology.org/ontology/MESH/C023140 http://purl.bioontology.org/ontology/MESH/C101782 http://purl.bioontology.org/ontology/MESH/C000627558 http://purl.bioontology.org/ontology/MESH/C575162 http://purl.bioontology.org/ontology/MESH/C575163 http://purl.bioontology.org/ontology/MESH/C026691 http://purl.bioontology.org/ontology/MESH/C112338 http://purl.bioontology.org/ontology/MESH/C404184 http://purl.bioontology.org/ontology/MESH/C109534 http://purl.bioontology.org/ontology/MESH/C496086 http://purl.bioontology.org/ontology/MESH/C463461 http://purl.bioontology.org/ontology/MESH/C070792 http://purl.bioontology.org/ontology/MESH/C043417 http://purl.bioontology.org/ontology/MESH/C503462 http://purl.bioontology.org/ontology/MESH/C544932 http://purl.bioontology.org/ontology/MESH/C487545 http://purl.bioontology.org/ontology/MESH/C407743 http://purl.bioontology.org/ontology/MESH/C522758 http://purl.bioontology.org/ontology/MESH/C055218 http://purl.bioontology.org/ontology/MESH/C446929 http://purl.bioontology.org/ontology/MESH/C118285 http://purl.bioontology.org/ontology/MESH/C486862 http://purl.bioontology.org/ontology/MESH/C118225 http://purl.bioontology.org/ontology/MESH/C078202 http://purl.bioontology.org/ontology/MESH/C000626770 http://purl.bioontology.org/ontology/MESH/C108542 http://purl.bioontology.org/ontology/MESH/C546205 http://purl.bioontology.org/ontology/MESH/C000603999 http://purl.bioontology.org/ontology/MESH/C585937 http://purl.bioontology.org/ontology/MESH/C069983 http://purl.bioontology.org/ontology/MESH/C107915 http://purl.bioontology.org/ontology/MESH/C083202 http://purl.bioontology.org/ontology/MESH/C118146 http://purl.bioontology.org/ontology/MESH/C070331 http://purl.bioontology.org/ontology/MESH/C092219 http://purl.bioontology.org/ontology/MESH/C000624446 http://purl.bioontology.org/ontology/MESH/C544492 http://purl.bioontology.org/ontology/MESH/C101162 http://purl.bioontology.org/ontology/MESH/C530191 http://purl.bioontology.org/ontology/MESH/C504536 http://purl.bioontology.org/ontology/MESH/C062255 http://purl.bioontology.org/ontology/MESH/C494221 http://purl.bioontology.org/ontology/MESH/C436950 http://purl.bioontology.org/ontology/MESH/C415702 http://purl.bioontology.org/ontology/MESH/C000624447 http://purl.bioontology.org/ontology/MESH/C092602 http://purl.bioontology.org/ontology/MESH/C034970 http://purl.bioontology.org/ontology/MESH/C068508 http://purl.bioontology.org/ontology/MESH/C093010 http://purl.bioontology.org/ontology/MESH/C105117 http://purl.bioontology.org/ontology/MESH/C090592 http://purl.bioontology.org/ontology/MESH/C479807 http://purl.bioontology.org/ontology/MESH/C072146 http://purl.bioontology.org/ontology/MESH/C425929 http://purl.bioontology.org/ontology/MESH/C511743 http://purl.bioontology.org/ontology/MESH/C520218 http://purl.bioontology.org/ontology/MESH/C404302 http://purl.bioontology.org/ontology/MESH/C120926 http://purl.bioontology.org/ontology/MESH/C429004 http://purl.bioontology.org/ontology/MESH/C083980 http://purl.bioontology.org/ontology/MESH/C482399
MDA	19760419
MMR	20200527
MN	D08.811.913.696.445.308.300
notation	D004259
prefLabel	DNA-Directed DNA Polymerase
RR	9012-90-2 (CAS RN)
TERMUI	T012946 T012947 T012948 T012949 T000996227
TH	NLM (1977) UNK (19XX) NLM (2021) NLM (1998)
tui	T116 T126
subClassOf	http://purl.bioontology.org/ontology/MESH/D004254

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/NDFRT/N0000168286	NDFRT	CUI
http://purl.bioontology.org/ontology/CSP/2112-4320	CRISP	CUI
http://purl.bioontology.org/ontology/MSHFRE/D004259	MSHFRE	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/36387003	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SNMI/F-694B8	SNMI	CUI
http://purl.bioontology.org/ontology/LNC/LP71564-6	LOINC	CUI
http://purl.bioontology.org/ontology/SCTSPA/36387003	SCTSPA	CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D08.811.913.696.445.308.300	RH-MESH	LOOM
http://purl.bioontology.org/ontology/CSP/2112-4320	CRISP	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00020423	PMAPP-PMO	LOOM
http://purl.obolibrary.org/obo/MESH_D004259	BERO	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16512	NCIT	LOOM
http://purl.obolibrary.org/obo/NCIT_C16512	BERO	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/36387003	SNOMEDCT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D004259	RH-MESH	LOOM
http://purl.bioontology.org/ontology/SNMI/F-694B8	SNMI	LOOM
http://purl.obolibrary.org/obo/OMIT_0005516	OMIT	LOOM