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Last uploaded: January 31, 2024

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Preferred Name	Diphosphonates
Synonyms	Bisphosphonates Bisphosphonate
Definitions	Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.
ID	http://purl.bioontology.org/ontology/MESH/D004164
altLabel	Bisphosphonates Bisphosphonate
AQL	AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0012544
DC	1
definition	Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.
DX	19770101
HN	77
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	0
isa	http://purl.bioontology.org/ontology/MESH/D050071
Machine permutation	77
Mapped from	http://purl.bioontology.org/ontology/MESH/C043715 http://purl.bioontology.org/ontology/MESH/C528986 http://purl.bioontology.org/ontology/MESH/C532846 http://purl.bioontology.org/ontology/MESH/C542313 http://purl.bioontology.org/ontology/MESH/C403881 http://purl.bioontology.org/ontology/MESH/C403880 http://purl.bioontology.org/ontology/MESH/C090916 http://purl.bioontology.org/ontology/MESH/C057041 http://purl.bioontology.org/ontology/MESH/C471708 http://purl.bioontology.org/ontology/MESH/C087958 http://purl.bioontology.org/ontology/MESH/C574211 http://purl.bioontology.org/ontology/MESH/C461200 http://purl.bioontology.org/ontology/MESH/C069435 http://purl.bioontology.org/ontology/MESH/C118560 http://purl.bioontology.org/ontology/MESH/C413900 http://purl.bioontology.org/ontology/MESH/C413901 http://purl.bioontology.org/ontology/MESH/C084620 http://purl.bioontology.org/ontology/MESH/C033905 http://purl.bioontology.org/ontology/MESH/C410028 http://purl.bioontology.org/ontology/MESH/C000621092 http://purl.bioontology.org/ontology/MESH/C008791 http://purl.bioontology.org/ontology/MESH/C118890 http://purl.bioontology.org/ontology/MESH/C039738 http://purl.bioontology.org/ontology/MESH/C406720 http://purl.bioontology.org/ontology/MESH/C427505 http://purl.bioontology.org/ontology/MESH/C427504 http://purl.bioontology.org/ontology/MESH/C427503 http://purl.bioontology.org/ontology/MESH/C000595745 http://purl.bioontology.org/ontology/MESH/C048432 http://purl.bioontology.org/ontology/MESH/C109548 http://purl.bioontology.org/ontology/MESH/C058568 http://purl.bioontology.org/ontology/MESH/C061154 http://purl.bioontology.org/ontology/MESH/C000595746 http://purl.bioontology.org/ontology/MESH/C000592733 http://purl.bioontology.org/ontology/MESH/C487584 http://purl.bioontology.org/ontology/MESH/C419686 http://purl.bioontology.org/ontology/MESH/C062324 http://purl.bioontology.org/ontology/MESH/C087308 http://purl.bioontology.org/ontology/MESH/C054782 http://purl.bioontology.org/ontology/MESH/C023571 http://purl.bioontology.org/ontology/MESH/C023572 http://purl.bioontology.org/ontology/MESH/C023573 http://purl.bioontology.org/ontology/MESH/C470920 http://purl.bioontology.org/ontology/MESH/C078699 http://purl.bioontology.org/ontology/MESH/C525211 http://purl.bioontology.org/ontology/MESH/C525210 http://purl.bioontology.org/ontology/MESH/C000589726 http://purl.bioontology.org/ontology/MESH/C528502 http://purl.bioontology.org/ontology/MESH/C098121 http://purl.bioontology.org/ontology/MESH/C000716218 http://purl.bioontology.org/ontology/MESH/C516445 http://purl.bioontology.org/ontology/MESH/C538827 http://purl.bioontology.org/ontology/MESH/C071542 http://purl.bioontology.org/ontology/MESH/C561885 http://purl.bioontology.org/ontology/MESH/C520637 http://purl.bioontology.org/ontology/MESH/C518651 http://purl.bioontology.org/ontology/MESH/C562025 http://purl.bioontology.org/ontology/MESH/C000595744 http://purl.bioontology.org/ontology/MESH/C108156 http://purl.bioontology.org/ontology/MESH/C114890 http://purl.bioontology.org/ontology/MESH/C055366 http://purl.bioontology.org/ontology/MESH/C583427 http://purl.bioontology.org/ontology/MESH/C097566 http://purl.bioontology.org/ontology/MESH/C000624633 http://purl.bioontology.org/ontology/MESH/C517229 http://purl.bioontology.org/ontology/MESH/C000622390 http://purl.bioontology.org/ontology/MESH/C525470 http://purl.bioontology.org/ontology/MESH/C065509 http://purl.bioontology.org/ontology/MESH/C446302 http://purl.bioontology.org/ontology/MESH/C088378 http://purl.bioontology.org/ontology/MESH/C118445 http://purl.bioontology.org/ontology/MESH/C016514 http://purl.bioontology.org/ontology/MESH/C533033 http://purl.bioontology.org/ontology/MESH/C512981 http://purl.bioontology.org/ontology/MESH/C512982 http://purl.bioontology.org/ontology/MESH/C053162 http://purl.bioontology.org/ontology/MESH/C417558 http://purl.bioontology.org/ontology/MESH/C417557 http://purl.bioontology.org/ontology/MESH/C052434 http://purl.bioontology.org/ontology/MESH/C059662 http://purl.bioontology.org/ontology/MESH/C413184 http://purl.bioontology.org/ontology/MESH/C407151 http://purl.bioontology.org/ontology/MESH/C035780 http://purl.bioontology.org/ontology/MESH/C104510 http://purl.bioontology.org/ontology/MESH/C056654 http://purl.bioontology.org/ontology/MESH/C056653 http://purl.bioontology.org/ontology/MESH/C541516 http://purl.bioontology.org/ontology/MESH/C514497 http://purl.bioontology.org/ontology/MESH/C025458 http://purl.bioontology.org/ontology/MESH/C055246 http://purl.bioontology.org/ontology/MESH/C517422 http://purl.bioontology.org/ontology/MESH/C074668 http://purl.bioontology.org/ontology/MESH/C074667 http://purl.bioontology.org/ontology/MESH/C039598 http://purl.bioontology.org/ontology/MESH/C110765 http://purl.bioontology.org/ontology/MESH/C108384 http://purl.bioontology.org/ontology/MESH/C108383 http://purl.bioontology.org/ontology/MESH/C000718571 http://purl.bioontology.org/ontology/MESH/C015512 http://purl.bioontology.org/ontology/MESH/C027474 http://purl.bioontology.org/ontology/MESH/C411447 http://purl.bioontology.org/ontology/MESH/C054229 http://purl.bioontology.org/ontology/MESH/C093436 http://purl.bioontology.org/ontology/MESH/C118184 http://purl.bioontology.org/ontology/MESH/C109992 http://purl.bioontology.org/ontology/MESH/C058651 http://purl.bioontology.org/ontology/MESH/C055774 http://purl.bioontology.org/ontology/MESH/C026182 http://purl.bioontology.org/ontology/MESH/C026181 http://purl.bioontology.org/ontology/MESH/C000588614 http://purl.bioontology.org/ontology/MESH/C409217 http://purl.bioontology.org/ontology/MESH/C078046 http://purl.bioontology.org/ontology/MESH/C517542 http://purl.bioontology.org/ontology/MESH/C517543 http://purl.bioontology.org/ontology/MESH/C057370 http://purl.bioontology.org/ontology/MESH/C546599 http://purl.bioontology.org/ontology/MESH/C526809 http://purl.bioontology.org/ontology/MESH/C434766 http://purl.bioontology.org/ontology/MESH/C525206 http://purl.bioontology.org/ontology/MESH/C479078 http://purl.bioontology.org/ontology/MESH/C069495 http://purl.bioontology.org/ontology/MESH/C069494 http://purl.bioontology.org/ontology/MESH/C000594599 http://purl.bioontology.org/ontology/MESH/C046461 http://purl.bioontology.org/ontology/MESH/C053389 http://purl.bioontology.org/ontology/MESH/C000626805 http://purl.bioontology.org/ontology/MESH/C046515 http://purl.bioontology.org/ontology/MESH/C100355 http://purl.bioontology.org/ontology/MESH/C466062 http://purl.bioontology.org/ontology/MESH/C013954 http://purl.bioontology.org/ontology/MESH/C098473 http://purl.bioontology.org/ontology/MESH/C516039 http://purl.bioontology.org/ontology/MESH/C000610711 http://purl.bioontology.org/ontology/MESH/C522848 http://purl.bioontology.org/ontology/MESH/C122003 http://purl.bioontology.org/ontology/MESH/C587916 http://purl.bioontology.org/ontology/MESH/C045541 http://purl.bioontology.org/ontology/MESH/C029285 http://purl.bioontology.org/ontology/MESH/C055940 http://purl.bioontology.org/ontology/MESH/C122126 http://purl.bioontology.org/ontology/MESH/C508315 http://purl.bioontology.org/ontology/MESH/C402281 http://purl.bioontology.org/ontology/MESH/C060491 http://purl.bioontology.org/ontology/MESH/C415154 http://purl.bioontology.org/ontology/MESH/C079103 http://purl.bioontology.org/ontology/MESH/C029045 http://purl.bioontology.org/ontology/MESH/C501481 http://purl.bioontology.org/ontology/MESH/C110479 http://purl.bioontology.org/ontology/MESH/C031876
MDA	19760416
MMR	20200527
MN	D02.705.429.500
notation	D004164
PA	D050071
prefLabel	Diphosphonates
TERMUI	T012653 T012654 T000996208
TH	NLM (1977) NLM (1990) NLM (2021)
tui	T109 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D063065

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/MSHFRE/D004164	MSHFRE	CUI
http://purl.bioontology.org/ontology/RCD/fo...	RCD	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/96281001	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SCTSPA/372907000	SCTSPA	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000007707	NDFRT	CUI
http://purl.bioontology.org/ontology/SCTSPA/96281001	SCTSPA	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/372907000	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SNMI/C-71810	SNMI	CUI
http://purl.bioontology.org/ontology/CSP/2297-4218	CRISP	CUI
http://www.phoc.org.cn/pmo/class/PMO_00017331	PMAPP-PMO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3985	OCHV	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.705.429.500	RH-MESH	LOOM
http://purl.obolibrary.org/obo/OMIT_0005427	OMIT	LOOM
http://id.nlm.nih.gov/mesh/D004164	MDM	LOOM
http://www.owl-ontologies.com/assert.owl#Diphosphonates	ONTOKBCF	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D004164	RH-MESH	LOOM
http://purl.obolibrary.org/obo/MESH_D004164	BERO	LOOM