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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D003961
http://purl.bioontology.org/ontology/MESH/D003961
|
|---|---|
| Preferred Name | Dianhydrogalactitol |
| Definitions |
One of the cytotoxic dihalohexitols that alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in a disruption of DNA function and cell cycle arrest. It has antineoplastic activity and also causes bone marrow toxicity.
|
| Synonyms |
1,2,5,6-Dianhydrogalactitol
Dianhydrodulcitol
NSC 132313
NSC-132313
Diepoxygalactitol
NSC132313
1,2-5,6-Dianhydrogalactitol
Galactitol, 1,2:5,6-dianhydro-
Diepoxydulcitol
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | One of the cytotoxic dihalohexitols that alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in a disruption of DNA function and cell cycle arrest. It has antineoplastic activity and also causes bone marrow toxicity. |
|---|---|
| altLabel |
1,2,5,6-Dianhydrogalactitol
Dianhydrodulcitol
NSC 132313
NSC-132313
Diepoxygalactitol
NSC132313
1,2-5,6-Dianhydrogalactitol
Galactitol, 1,2:5,6-dianhydro-
Diepoxydulcitol
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|
| prefLabel | Dianhydrogalactitol
|
| Machine permutation | 91; was see under SUGAR ALCOHOLS 1979-90
|
| HN | 91(79); was see under SUGAR ALCOHOLS 1979-90
|
| Mapped from | |
| type | |
| isa | |
| PA | D018906
|
| tui |
T109
T121
|
| TERMUI |
T000941632
T012005
T012000
T012001
T012002
T012003
T012004
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|
| TH |
NLM (1979)
FDA SRS (2014)
UNK (19XX)
NLM (2017)
|
| MMR | 20180702
|
| notation | D003961
|
| Semantic type UMLS property | |
| RR | 23261-20-3 (Dianhydrogalactitol)
|
| Inverse of AQ |
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|
| DX | 19910101
|
| cui |
C0011967
C0878282
|
| DC | 1
|
| MN |
D02.033.800.400.350
D09.853.400.350
|
| AQL | AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
|
| Inverse of RB |
4S465RYF7M
0
|
| MDA | 19990101
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |