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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D003185
http://purl.bioontology.org/ontology/MESH/D003185
|
|---|---|
| Preferred Name | Complement C8 |
| Definitions |
A 150-kDa serum glycoprotein composed of three subunits with each encoded by a different gene (C8A; C8B; and C8G). This heterotrimer contains a disulfide-linked C8alpha-C8gamma heterodimer and a noncovalently associated C8beta chain. C8 is the next component to bind the C5-7 complex forming C5b-8 that binds COMPLEMENT C9 and acts as a catalyst in the polymerization of C9.
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| Synonyms |
Complement Component C8 alpha
Complement Component C8 gamma Chain
Complement Component C8 gamma
Complement, C8
Complement Component C8 alpha Chain
Complement Component C8 beta
Component 8, Complement
C8, Complement
Complement 8
Complement Component 8
C8 Complement
Complement Component C8 beta Chain
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A 150-kDa serum glycoprotein composed of three subunits with each encoded by a different gene (C8A; C8B; and C8G). This heterotrimer contains a disulfide-linked C8alpha-C8gamma heterodimer and a noncovalently associated C8beta chain. C8 is the next component to bind the C5-7 complex forming C5b-8 that binds COMPLEMENT C9 and acts as a catalyst in the polymerization of C9. |
|---|---|
| altLabel |
Complement Component C8 alpha
Complement Component C8 gamma Chain
Complement Component C8 gamma
Complement, C8
Complement Component C8 alpha Chain
Complement Component C8 beta
Component 8, Complement
C8, Complement
Complement 8
Complement Component 8
C8 Complement
Complement Component C8 beta Chain
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| prefLabel | Complement C8
|
| Machine permutation | 2006; see COMPLEMENT 8 1978-2005; see COMPLEMENT 1975-1977
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| HN | 2006 (1975)
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| Mapped from | |
| type | |
| isa | |
| PA | D007155
|
| tui |
T116
T129
|
| TERMUI |
T624072
T624073
T624069
T624074
T624071
T009302
T624060
T631392
T624061
T624070
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| TH |
NLM (1975)
NLM (2006)
|
| MMR | 20050630
|
| notation | D003185
|
| Semantic type UMLS property | |
| Inverse of AQ |
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| DX | 19780101
|
| cui |
C1564602
C0009525
C1564601
C1564603
|
| DC | 1
|
| MN | D12.776.124.486.274.750
|
| AQL | AD AE AG AI AN BI CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
|
| Inverse of RB | 0
|
| MDA | 20041214
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |