Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D002945 http://purl.bioontology.org/ontology/MESH/D002945
Preferred Name	Cisplatin
Definitions	An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
Synonyms	Platinum Diamminodichloride Platino Diamminodichloride, Platinum NSC-119875 Platidiam cis-Diamminedichloroplatinum(II) cis-Dichlorodiammineplatinum(II) cis-Diamminedichloroplatinum cis-Platinum cis Platinum Biocisplatinum cis Diamminedichloroplatinum Platinol Platinum, diamminedichloro-, (SP-4-2)- Dichlorodiammineplatinum See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
altLabel	Platinum Diamminodichloride Platino Diamminodichloride, Platinum NSC-119875 Platidiam cis-Diamminedichloroplatinum(II) cis-Dichlorodiammineplatinum(II) cis-Diamminedichloroplatinum cis-Platinum cis Platinum Biocisplatinum cis Diamminedichloroplatinum Platinol Platinum, diamminedichloro-, (SP-4-2)- Dichlorodiammineplatinum See more See less
prefLabel	Cisplatin
Machine permutation	84; was see under DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1981-83; was PLATINUM DIAMMINODICHLORIDE see under DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1974-80; DIAMMONIUM CHLOROPLATINUM COMPOUNDS was heading 1974-83
HN	84(81); was see under DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1981-83; was PLATINUM DIAMMINODICHLORIDE see under DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1974-80; DIAMMONIUM CHLOROPLATINUM COMPOUNDS was heading 1974-83
Mapped from	http://purl.bioontology.org/ontology/MESH/C097979 http://purl.bioontology.org/ontology/MESH/C061125 http://purl.bioontology.org/ontology/MESH/C053712 http://purl.bioontology.org/ontology/MESH/C053713 http://purl.bioontology.org/ontology/MESH/C429754 http://purl.bioontology.org/ontology/MESH/C110743 http://purl.bioontology.org/ontology/MESH/C075175 http://purl.bioontology.org/ontology/MESH/C048472 http://purl.bioontology.org/ontology/MESH/C044361 http://purl.bioontology.org/ontology/MESH/C079337 http://purl.bioontology.org/ontology/MESH/C102002 http://purl.bioontology.org/ontology/MESH/C048391 http://purl.bioontology.org/ontology/MESH/C045346 http://purl.bioontology.org/ontology/MESH/C104403 http://purl.bioontology.org/ontology/MESH/C040393 http://purl.bioontology.org/ontology/MESH/C067284 http://purl.bioontology.org/ontology/MESH/C036046 http://purl.bioontology.org/ontology/MESH/C075609 http://purl.bioontology.org/ontology/MESH/C034084 http://purl.bioontology.org/ontology/MESH/C034909 http://purl.bioontology.org/ontology/MESH/C034904 http://purl.bioontology.org/ontology/MESH/C034908 http://purl.bioontology.org/ontology/MESH/C034859 http://purl.bioontology.org/ontology/MESH/C092463 http://purl.bioontology.org/ontology/MESH/C065462 http://purl.bioontology.org/ontology/MESH/C413422 http://purl.bioontology.org/ontology/MESH/C087494 http://purl.bioontology.org/ontology/MESH/C053039 http://purl.bioontology.org/ontology/MESH/C063992 http://purl.bioontology.org/ontology/MESH/C099766 http://purl.bioontology.org/ontology/MESH/C110509 http://purl.bioontology.org/ontology/MESH/C058139 http://purl.bioontology.org/ontology/MESH/C048382 http://purl.bioontology.org/ontology/MESH/C094165 http://purl.bioontology.org/ontology/MESH/C096751 http://purl.bioontology.org/ontology/MESH/C068920 http://purl.bioontology.org/ontology/MESH/C043227 http://purl.bioontology.org/ontology/MESH/C416122 http://purl.bioontology.org/ontology/MESH/C081461 http://purl.bioontology.org/ontology/MESH/C411257 http://purl.bioontology.org/ontology/MESH/C085789 http://purl.bioontology.org/ontology/MESH/C000717879 http://purl.bioontology.org/ontology/MESH/C031178 http://purl.bioontology.org/ontology/MESH/C099816 http://purl.bioontology.org/ontology/MESH/C085328 http://purl.bioontology.org/ontology/MESH/C065401 http://purl.bioontology.org/ontology/MESH/C083092 http://purl.bioontology.org/ontology/MESH/C087163 http://purl.bioontology.org/ontology/MESH/C110432 http://purl.bioontology.org/ontology/MESH/C042322 http://purl.bioontology.org/ontology/MESH/C072477 http://purl.bioontology.org/ontology/MESH/C070949 http://purl.bioontology.org/ontology/MESH/C055497 http://purl.bioontology.org/ontology/MESH/C070666 http://purl.bioontology.org/ontology/MESH/C070665 http://purl.bioontology.org/ontology/MESH/C042306 http://purl.bioontology.org/ontology/MESH/C042305 http://purl.bioontology.org/ontology/MESH/C045968 http://purl.bioontology.org/ontology/MESH/C000711476 http://purl.bioontology.org/ontology/MESH/C451334 http://purl.bioontology.org/ontology/MESH/C485286 http://purl.bioontology.org/ontology/MESH/C071786 http://purl.bioontology.org/ontology/MESH/C070611 http://purl.bioontology.org/ontology/MESH/C057623 http://purl.bioontology.org/ontology/MESH/C057624 http://purl.bioontology.org/ontology/MESH/C016468 http://purl.bioontology.org/ontology/MESH/C088030 http://purl.bioontology.org/ontology/MESH/C056644 http://purl.bioontology.org/ontology/MESH/C056642 http://purl.bioontology.org/ontology/MESH/C432844 http://purl.bioontology.org/ontology/MESH/C059770 http://purl.bioontology.org/ontology/MESH/C097008 http://purl.bioontology.org/ontology/MESH/C073578 http://purl.bioontology.org/ontology/MESH/C503131 http://purl.bioontology.org/ontology/MESH/C445334 http://purl.bioontology.org/ontology/MESH/C078724 http://purl.bioontology.org/ontology/MESH/C062713 http://purl.bioontology.org/ontology/MESH/C040622 http://purl.bioontology.org/ontology/MESH/C079611 http://purl.bioontology.org/ontology/MESH/C079610 http://purl.bioontology.org/ontology/MESH/C044837 http://purl.bioontology.org/ontology/MESH/C111758 http://purl.bioontology.org/ontology/MESH/C111757 http://purl.bioontology.org/ontology/MESH/C110053 http://purl.bioontology.org/ontology/MESH/C066002 http://purl.bioontology.org/ontology/MESH/C454400 http://purl.bioontology.org/ontology/MESH/C061181 http://purl.bioontology.org/ontology/MESH/C102420 http://purl.bioontology.org/ontology/MESH/C038809 http://purl.bioontology.org/ontology/MESH/C065095 http://purl.bioontology.org/ontology/MESH/C080658 http://purl.bioontology.org/ontology/MESH/C096480 http://purl.bioontology.org/ontology/MESH/C047598 http://purl.bioontology.org/ontology/MESH/C060376 http://purl.bioontology.org/ontology/MESH/C034297 http://purl.bioontology.org/ontology/MESH/C034492 http://purl.bioontology.org/ontology/MESH/C092984 http://purl.bioontology.org/ontology/MESH/C429383 http://purl.bioontology.org/ontology/MESH/C064603 http://purl.bioontology.org/ontology/MESH/C044627 http://purl.bioontology.org/ontology/MESH/C044626 http://purl.bioontology.org/ontology/MESH/C069294 http://purl.bioontology.org/ontology/MESH/C069295 http://purl.bioontology.org/ontology/MESH/C470178 http://purl.bioontology.org/ontology/MESH/C032799 http://purl.bioontology.org/ontology/MESH/C094851 http://purl.bioontology.org/ontology/MESH/C408045 http://purl.bioontology.org/ontology/MESH/C104032 http://purl.bioontology.org/ontology/MESH/C403589 http://purl.bioontology.org/ontology/MESH/C476718 http://purl.bioontology.org/ontology/MESH/C068760 http://purl.bioontology.org/ontology/MESH/C060798 http://purl.bioontology.org/ontology/MESH/C418366 http://purl.bioontology.org/ontology/MESH/C057270 http://purl.bioontology.org/ontology/MESH/C039633 http://purl.bioontology.org/ontology/MESH/C068823 http://purl.bioontology.org/ontology/MESH/C073984 http://purl.bioontology.org/ontology/MESH/C052859 http://purl.bioontology.org/ontology/MESH/C411086 http://purl.bioontology.org/ontology/MESH/C050434 http://purl.bioontology.org/ontology/MESH/C090904 http://purl.bioontology.org/ontology/MESH/C105624 http://purl.bioontology.org/ontology/MESH/C082742 http://purl.bioontology.org/ontology/MESH/C034483 http://purl.bioontology.org/ontology/MESH/C051760 http://purl.bioontology.org/ontology/MESH/C432684 http://purl.bioontology.org/ontology/MESH/C039512 http://purl.bioontology.org/ontology/MESH/C482176 http://purl.bioontology.org/ontology/MESH/C543033 http://purl.bioontology.org/ontology/MESH/C075766 http://purl.bioontology.org/ontology/MESH/C043804 http://purl.bioontology.org/ontology/MESH/C112982 http://purl.bioontology.org/ontology/MESH/C082081 http://purl.bioontology.org/ontology/MESH/C488282 http://purl.bioontology.org/ontology/MESH/C059289 http://purl.bioontology.org/ontology/MESH/C400981 http://purl.bioontology.org/ontology/MESH/C087705 http://purl.bioontology.org/ontology/MESH/C101573 http://purl.bioontology.org/ontology/MESH/C057922 http://purl.bioontology.org/ontology/MESH/C038820 http://purl.bioontology.org/ontology/MESH/C411288 http://purl.bioontology.org/ontology/MESH/C111043 http://purl.bioontology.org/ontology/MESH/C408984 http://purl.bioontology.org/ontology/MESH/C091469 http://purl.bioontology.org/ontology/MESH/C484028 http://purl.bioontology.org/ontology/MESH/C110661 http://purl.bioontology.org/ontology/MESH/C071552 http://purl.bioontology.org/ontology/MESH/C037510 http://purl.bioontology.org/ontology/MESH/C091884 http://purl.bioontology.org/ontology/MESH/C104874 http://purl.bioontology.org/ontology/MESH/C059163 http://purl.bioontology.org/ontology/MESH/C046870 http://purl.bioontology.org/ontology/MESH/C448581 http://purl.bioontology.org/ontology/MESH/C448580 http://purl.bioontology.org/ontology/MESH/C080222 http://purl.bioontology.org/ontology/MESH/C427583 http://purl.bioontology.org/ontology/MESH/C053518 http://purl.bioontology.org/ontology/MESH/C051133 http://purl.bioontology.org/ontology/MESH/C072526 http://purl.bioontology.org/ontology/MESH/C401502 http://purl.bioontology.org/ontology/MESH/C401501 http://purl.bioontology.org/ontology/MESH/C401503 http://purl.bioontology.org/ontology/MESH/C043623 http://purl.bioontology.org/ontology/MESH/C067247 http://purl.bioontology.org/ontology/MESH/C046428 http://purl.bioontology.org/ontology/MESH/C445781 http://purl.bioontology.org/ontology/MESH/C110518 http://purl.bioontology.org/ontology/MESH/C452190 http://purl.bioontology.org/ontology/MESH/C049560 http://purl.bioontology.org/ontology/MESH/C066826 http://purl.bioontology.org/ontology/MESH/C048526 http://purl.bioontology.org/ontology/MESH/C038536 http://purl.bioontology.org/ontology/MESH/C410217 http://purl.bioontology.org/ontology/MESH/C068487 http://purl.bioontology.org/ontology/MESH/C066689 http://purl.bioontology.org/ontology/MESH/C041149 http://purl.bioontology.org/ontology/MESH/C417382 http://purl.bioontology.org/ontology/MESH/C094059 http://purl.bioontology.org/ontology/MESH/C084946 http://purl.bioontology.org/ontology/MESH/C042812 http://purl.bioontology.org/ontology/MESH/C118314 http://purl.bioontology.org/ontology/MESH/C108271 http://purl.bioontology.org/ontology/MESH/C529375 http://purl.bioontology.org/ontology/MESH/C062042 http://purl.bioontology.org/ontology/MESH/C099913 http://purl.bioontology.org/ontology/MESH/C057159 http://purl.bioontology.org/ontology/MESH/C048855 http://purl.bioontology.org/ontology/MESH/C096142 http://purl.bioontology.org/ontology/MESH/C091014 http://purl.bioontology.org/ontology/MESH/C091013 http://purl.bioontology.org/ontology/MESH/C055285 http://purl.bioontology.org/ontology/MESH/C093277 http://purl.bioontology.org/ontology/MESH/C034868 http://purl.bioontology.org/ontology/MESH/C062400 http://purl.bioontology.org/ontology/MESH/C089162 http://purl.bioontology.org/ontology/MESH/C403294 http://purl.bioontology.org/ontology/MESH/C439730 http://purl.bioontology.org/ontology/MESH/C037371 http://purl.bioontology.org/ontology/MESH/C073824 http://purl.bioontology.org/ontology/MESH/C465960 http://purl.bioontology.org/ontology/MESH/C438724 http://purl.bioontology.org/ontology/MESH/C037901 http://purl.bioontology.org/ontology/MESH/C037900 http://purl.bioontology.org/ontology/MESH/C090539 http://purl.bioontology.org/ontology/MESH/C411764 http://purl.bioontology.org/ontology/MESH/C047587 http://purl.bioontology.org/ontology/MESH/C047586 http://purl.bioontology.org/ontology/MESH/C076361 http://purl.bioontology.org/ontology/MESH/C051719 http://purl.bioontology.org/ontology/MESH/C058575 http://purl.bioontology.org/ontology/MESH/C094992 http://purl.bioontology.org/ontology/MESH/C402728 http://purl.bioontology.org/ontology/MESH/C095424 http://purl.bioontology.org/ontology/MESH/C095423 http://purl.bioontology.org/ontology/MESH/C095425 http://purl.bioontology.org/ontology/MESH/C048362 http://purl.bioontology.org/ontology/MESH/C452319 http://purl.bioontology.org/ontology/MESH/C061422 http://purl.bioontology.org/ontology/MESH/C052860 http://purl.bioontology.org/ontology/MESH/C054153 http://purl.bioontology.org/ontology/MESH/C092424 http://purl.bioontology.org/ontology/MESH/C075196 http://purl.bioontology.org/ontology/MESH/C082618 http://purl.bioontology.org/ontology/MESH/C056638 http://purl.bioontology.org/ontology/MESH/C118836 http://purl.bioontology.org/ontology/MESH/C099563 http://purl.bioontology.org/ontology/MESH/C059009 http://purl.bioontology.org/ontology/MESH/C050440 http://purl.bioontology.org/ontology/MESH/C403746 http://purl.bioontology.org/ontology/MESH/C040538 http://purl.bioontology.org/ontology/MESH/C087720 http://purl.bioontology.org/ontology/MESH/C411476 http://purl.bioontology.org/ontology/MESH/C074841 http://purl.bioontology.org/ontology/MESH/C083526 http://purl.bioontology.org/ontology/MESH/C072926 http://purl.bioontology.org/ontology/MESH/C071963 http://purl.bioontology.org/ontology/MESH/C053730 http://purl.bioontology.org/ontology/MESH/C112530 http://purl.bioontology.org/ontology/MESH/C542926 http://purl.bioontology.org/ontology/MESH/C079632 http://purl.bioontology.org/ontology/MESH/C064163 http://purl.bioontology.org/ontology/MESH/C038357 http://purl.bioontology.org/ontology/MESH/C056512 http://purl.bioontology.org/ontology/MESH/C120600 http://purl.bioontology.org/ontology/MESH/C060522 http://purl.bioontology.org/ontology/MESH/C074168 http://purl.bioontology.org/ontology/MESH/C074167 http://purl.bioontology.org/ontology/MESH/C080075 http://purl.bioontology.org/ontology/MESH/C045260 http://purl.bioontology.org/ontology/MESH/C074695 http://purl.bioontology.org/ontology/MESH/C065868 http://purl.bioontology.org/ontology/MESH/C095760 http://purl.bioontology.org/ontology/MESH/C034697 http://purl.bioontology.org/ontology/MESH/C080507 http://purl.bioontology.org/ontology/MESH/C422270 http://purl.bioontology.org/ontology/MESH/C056327 http://purl.bioontology.org/ontology/MESH/C056903 http://purl.bioontology.org/ontology/MESH/C484367 http://purl.bioontology.org/ontology/MESH/C058629 http://purl.bioontology.org/ontology/MESH/C002932 http://purl.bioontology.org/ontology/MESH/C038762 http://purl.bioontology.org/ontology/MESH/C430085 http://purl.bioontology.org/ontology/MESH/C076574 http://purl.bioontology.org/ontology/MESH/C113562 http://purl.bioontology.org/ontology/MESH/C087235 http://purl.bioontology.org/ontology/MESH/C044469 http://purl.bioontology.org/ontology/MESH/C044464 http://purl.bioontology.org/ontology/MESH/C121556 http://purl.bioontology.org/ontology/MESH/C078512 http://purl.bioontology.org/ontology/MESH/C039627 http://purl.bioontology.org/ontology/MESH/C094549 http://purl.bioontology.org/ontology/MESH/C045350 http://purl.bioontology.org/ontology/MESH/C050918 http://purl.bioontology.org/ontology/MESH/C066096 http://purl.bioontology.org/ontology/MESH/C071188 http://purl.bioontology.org/ontology/MESH/C063337 http://purl.bioontology.org/ontology/MESH/C057870 http://purl.bioontology.org/ontology/MESH/C406026 http://purl.bioontology.org/ontology/MESH/C045304 http://purl.bioontology.org/ontology/MESH/C409668 http://purl.bioontology.org/ontology/MESH/C066787 http://purl.bioontology.org/ontology/MESH/C038328 http://purl.bioontology.org/ontology/MESH/C040122 http://purl.bioontology.org/ontology/MESH/C068067 http://purl.bioontology.org/ontology/MESH/C055427 http://purl.bioontology.org/ontology/MESH/C055426 http://purl.bioontology.org/ontology/MESH/C112768 http://purl.bioontology.org/ontology/MESH/C461384 http://purl.bioontology.org/ontology/MESH/C049048 http://purl.bioontology.org/ontology/MESH/C042161 http://purl.bioontology.org/ontology/MESH/C113934 http://purl.bioontology.org/ontology/MESH/C404991 http://purl.bioontology.org/ontology/MESH/C118239 http://purl.bioontology.org/ontology/MESH/C037162 http://purl.bioontology.org/ontology/MESH/C045045 See more See less
type	http://www.w3.org/2002/07/owl#Class
isa	http://purl.bioontology.org/ontology/MESH/D011838 http://purl.bioontology.org/ontology/MESH/D000970 http://purl.bioontology.org/ontology/MESH/D003432
PA	D011838 D003432 D000970
tui	T197 T121
TERMUI	T008530 T008523 T008532 T008524 T008531 T008529 T008521 T008522 T008525 T008528 T008527 T008526 See more See less
TH	FDA SRS (2014) UNK (19XX) INN (19XX) USAN (1977) USP (19XX) BAN (19XX) See more See less
MMR	20130708
notation	D002945
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T121 http://purl.bioontology.org/ontology/STY/T197
RR	15663-27-1 (Cisplatin)
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
DX	19840101
cui	C0699665 C0699666 C0008838 C0699663 C0699664 C0936226 See more See less
DC	1
MN	D01.710.100 D01.625.125 D01.210.375
LT	TRD
AQL	AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
Inverse of RB	Q20Q21Q62J 0
OL	use CISPLATIN to search PLATINUM DIAMMINODICHLORIDE 1974-80 & DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1974-83
MDA	19990101
subClassOf	http://purl.bioontology.org/ontology/MESH/D017606 http://purl.bioontology.org/ontology/MESH/D017671 http://purl.bioontology.org/ontology/MESH/D017672

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