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Medical Subject Headings
Last uploaded:
January 16, 2025
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| Id | http://purl.bioontology.org/ontology/MESH/D002301
http://purl.bioontology.org/ontology/MESH/D002301
|
|---|---|
| Preferred Name | Cardiac Glycosides |
| Definitions |
Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.
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| Synonyms |
Cardiotonic Steroid
Cardiotonic Steroids
Glycosides, Cardiac
Steroids, Cardiotonic
Steroid, Cardiotonic
Cardiac Glycoside
Glycoside, Cardiac
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose. |
|---|---|
| altLabel |
Cardiotonic Steroid
Cardiotonic Steroids
Glycosides, Cardiac
Steroids, Cardiotonic
Steroid, Cardiotonic
Cardiac Glycoside
Glycoside, Cardiac
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| prefLabel |
Cardiac Glycosides
|
| TH |
NLM (1966)
UNK (19XX)
NLM (2021)
|
| notation |
D002301
|
| DX |
19660101
|
| MN |
D09.408.180
D04.210.500.155.580
|
| PA |
D004791
D002316
D000889
|
| MMR |
20200527
|
| Mapped from |
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|
| AQL |
AD AE AG AI AN BI BL CF CH CL CS EC GE HI IM IP ME PD PK PO RE SD ST TO TU UR
|
| subClassOf | |
| Semantic type UMLS property | |
| Inverse of RB |
0
|
| DC |
1
|
| MDA |
19990101
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| type | |
| tui |
T109
T121
|
| cui |
C0007158
|
| isa | |
| Inverse of AQ |
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|
| TERMUI |
T001005742
T001005743
T006613
T006614
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