Preferred Name | Captopril | |
Synonyms |
SQ14,534 SQ 14225 SQ 14534 SQ 14,534 Capoten SQ14225 SQ-14,534 L-Proline, 1-(3-mercapto-2-methyl-1-oxopropyl)-, (S)- SQ 14,225 SQ14534 Lopirin SQ-14225 SQ14,225 (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline SQ-14534 SQ-14,225 |
|
Definitions |
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin. |
|
ID |
http://purl.bioontology.org/ontology/MESH/D002216 |
|
altLabel |
SQ14,534 SQ 14225 SQ 14534 SQ 14,534 Capoten SQ14225 SQ-14,534 L-Proline, 1-(3-mercapto-2-methyl-1-oxopropyl)-, (S)- SQ 14,225 SQ14534 Lopirin SQ-14225 SQ14,225 (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline SQ-14534 SQ-14,225 |
|
AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
cui |
C0591224 C0733565 C0376291 C0006938 C0733566 |
|
DC |
1 |
|
definition |
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin. |
|
DX |
19860101 |
|
HN |
86(80); was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93 |
|
Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
Inverse of RB |
9G64RSX1XD 0 |
|
isa | ||
LT |
TRD |
|
Machine permutation |
86; was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93 |
|
Mapped from |
http://purl.bioontology.org/ontology/MESH/C041071 http://purl.bioontology.org/ontology/MESH/C053231 http://purl.bioontology.org/ontology/MESH/C065520 http://purl.bioontology.org/ontology/MESH/C070587 http://purl.bioontology.org/ontology/MESH/C046835 http://purl.bioontology.org/ontology/MESH/C060039 http://purl.bioontology.org/ontology/MESH/C035974 http://purl.bioontology.org/ontology/MESH/C046814 http://purl.bioontology.org/ontology/MESH/C069188 http://purl.bioontology.org/ontology/MESH/C044959 http://purl.bioontology.org/ontology/MESH/C044958 http://purl.bioontology.org/ontology/MESH/C053226 http://purl.bioontology.org/ontology/MESH/C053227 http://purl.bioontology.org/ontology/MESH/C038203 http://purl.bioontology.org/ontology/MESH/C048162 |
|
MDA |
19790523 |
|
MMR |
20130708 |
|
MN |
D12.125.072.401.623.270 |
|
notation |
D002216 |
|
OL |
use CAPTOPRIL to search SQ 14225 1980-93 |
|
PA |
D000959 D000806 |
|
prefLabel |
Captopril |
|
RR |
63250-36-2 ((R)-isomer) 62571-86-2 (Captopril) |
|
TERMUI |
T006333 T006338 T006336 T006334 T006335 T006332 T006337 T006339 |
|
TH |
NLM (1997) NLM (1996) FDA SRS (2014) NLM (1994) UNK (19XX) USAN (1978) INN (19XX) USP (19XX) BAN (19XX) |
|
tui |
T116 T121 |
|
subClassOf |