Medical Subject Headings

Last uploaded: August 28, 2024

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Preferred Name	Calmodulin
Synonyms	Protein Activator, Phosphodiesterase Activator Protein, Calcium-Dependent Protein, Calcium-Dependent Activator Protein, Bovine Activator Activator, Cyclic AMP-Phosphodiesterase Activator Protein, Phosphodiesterase Regulator, Calcium Dependent Calcium Dependent Activator Protein Calcium-Dependent Activator Protein Calcium-Dependent Regulator Phosphodiesterase Activator Protein Activating Factor, Phosphodiesterase Phosphodiesterase Protein Activator Regulator, Calcium-Dependent Phosphodiesterase Activating Factor Protein, Phosphodiesterase Activator Cyclic AMP-Phosphodiesterase Activator AMP-Phosphodiesterase Activator, Cyclic Activator Protein, Bovine Cyclic AMP Phosphodiesterase Activator Activator, Phosphodiesterase Protein Factor, Phosphodiesterase Activating Calcium Dependent Regulator Bovine Activator Protein
Definitions	A heat-stable, low-molecular-weight activator protein found mainly in the brain and heart. The binding of calcium ions to this protein allows this protein to bind to cyclic nucleotide phosphodiesterases and to adenyl cyclase with subsequent activation. Thereby this protein modulates cyclic AMP and cyclic GMP levels.
ID	http://purl.bioontology.org/ontology/MESH/D002147
altLabel	Protein Activator, Phosphodiesterase Activator Protein, Calcium-Dependent Protein, Calcium-Dependent Activator Protein, Bovine Activator Activator, Cyclic AMP-Phosphodiesterase Activator Protein, Phosphodiesterase Regulator, Calcium Dependent Calcium Dependent Activator Protein Calcium-Dependent Activator Protein Calcium-Dependent Regulator Phosphodiesterase Activator Protein Activating Factor, Phosphodiesterase Phosphodiesterase Protein Activator Regulator, Calcium-Dependent Phosphodiesterase Activating Factor Protein, Phosphodiesterase Activator Cyclic AMP-Phosphodiesterase Activator AMP-Phosphodiesterase Activator, Cyclic Activator Protein, Bovine Cyclic AMP Phosphodiesterase Activator Activator, Phosphodiesterase Protein Factor, Phosphodiesterase Activating Calcium Dependent Regulator Bovine Activator Protein
AN	a calcium-binding protein; /biosyn /physiol permitted
AQL	AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui	C0006772 C0006062 C0086081
DC	1
definition	A heat-stable, low-molecular-weight activator protein found mainly in the brain and heart. The binding of calcium ions to this protein allows this protein to bind to cyclic nucleotide phosphodiesterases and to adenyl cyclase with subsequent activation. Thereby this protein modulates cyclic AMP and cyclic GMP levels.
DX	19840101
HN	84; was CALCIUM-DEPENDENT REGULATOR see under CALCIUM-BINDING PROTEINS 1980-83; was CALCIUM-DEPENDENT REGULATOR see under CARRIER PROTEINS 1979
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	0
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D020013
Machine permutation	84; was CALCIUM-DEPENDENT REGULATOR see under CALCIUM-BINDING PROTEINS 1980-83; was CALCIUM-DEPENDENT REGULATOR see under CARRIER PROTEINS 1979
Mapped from	http://purl.bioontology.org/ontology/MESH/C035684 http://purl.bioontology.org/ontology/MESH/C082965 http://purl.bioontology.org/ontology/MESH/C037852 http://purl.bioontology.org/ontology/MESH/C090205 http://purl.bioontology.org/ontology/MESH/C040306 http://purl.bioontology.org/ontology/MESH/C552406 http://purl.bioontology.org/ontology/MESH/C552405 http://purl.bioontology.org/ontology/MESH/C000589340 http://purl.bioontology.org/ontology/MESH/C000607143 http://purl.bioontology.org/ontology/MESH/C054438 http://purl.bioontology.org/ontology/MESH/C056489 http://purl.bioontology.org/ontology/MESH/C579281 http://purl.bioontology.org/ontology/MESH/C541275 http://purl.bioontology.org/ontology/MESH/C404210 http://purl.bioontology.org/ontology/MESH/C404211 http://purl.bioontology.org/ontology/MESH/C518784 http://purl.bioontology.org/ontology/MESH/C056945 http://purl.bioontology.org/ontology/MESH/C488659 http://purl.bioontology.org/ontology/MESH/C036372 http://purl.bioontology.org/ontology/MESH/C448180 http://purl.bioontology.org/ontology/MESH/C082348 http://purl.bioontology.org/ontology/MESH/C505601 http://purl.bioontology.org/ontology/MESH/C041235 http://purl.bioontology.org/ontology/MESH/C542165 http://purl.bioontology.org/ontology/MESH/C073879 http://purl.bioontology.org/ontology/MESH/C056584 http://purl.bioontology.org/ontology/MESH/C428830 http://purl.bioontology.org/ontology/MESH/C046036 http://purl.bioontology.org/ontology/MESH/C000595843 http://purl.bioontology.org/ontology/MESH/C032602 http://purl.bioontology.org/ontology/MESH/C045187 http://purl.bioontology.org/ontology/MESH/C045186 http://purl.bioontology.org/ontology/MESH/C038199 http://purl.bioontology.org/ontology/MESH/C551040 http://purl.bioontology.org/ontology/MESH/C030955 http://purl.bioontology.org/ontology/MESH/C047030 http://purl.bioontology.org/ontology/MESH/C000622895 http://purl.bioontology.org/ontology/MESH/C000708728 http://purl.bioontology.org/ontology/MESH/C572690 http://purl.bioontology.org/ontology/MESH/C560300 http://purl.bioontology.org/ontology/MESH/C039906 http://purl.bioontology.org/ontology/MESH/C522735 http://purl.bioontology.org/ontology/MESH/C522736 http://purl.bioontology.org/ontology/MESH/C522737 http://purl.bioontology.org/ontology/MESH/C586315 http://purl.bioontology.org/ontology/MESH/C465133 http://purl.bioontology.org/ontology/MESH/C465132 http://purl.bioontology.org/ontology/MESH/C465131 http://purl.bioontology.org/ontology/MESH/C053993
MDA	19780308
MMR	20170630
MN	D12.776.157.125.412.249 D12.776.476.387.249 D12.644.360.372.249
notation	D002147
OL	use CALMODULIN to search CALCIUM-DEPENDENT REGULATOR 1979-83
prefLabel	Calmodulin
TERMUI	T006138 T006135 T006142 T006141 T006139 T006140 T006137 T006136 T006143
TH	NLM (1979) NLM (1992) UNK (19XX)
tui	T116 T123
subClassOf	http://purl.bioontology.org/ontology/MESH/D052139

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/SNMI/F-623D0	SNMI	CUI
http://purl.bioontology.org/ontology/MSHFRE/D002147	MSHFRE	CUI
http://purl.bioontology.org/ontology/MSHFRE/D002147	MSHFRE	CUI
http://purl.bioontology.org/ontology/MSHFRE/D002147	MSHFRE	CUI
http://purl.bioontology.org/ontology/CSP/2446-4200	CRISP	CUI
http://purl.bioontology.org/ontology/SCTSPA/41649004	SCTSPA	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000170618	NDFRT	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/41649004	SNOMEDCT	CUI
http://purl.org/obo/owlapi/fma#FMA_62343	BIOMODELS	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002147	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.360.381.249	RH-MESH	LOOM
http://purl.obolibrary.org/obo/PR_000004978	PR	LOOM
http://purl.obolibrary.org/obo/PR_000004978	INBANCIDO	LOOM
http://purl.obolibrary.org/obo/PR_000004978	CIDO	LOOM
http://purl.obolibrary.org/obo/PR_000004978	NIFSTD	LOOM
http://purl.obolibrary.org/obo/PR_000004978	GO-PLUS	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.476.387.249	RH-MESH	LOOM
http://purl.uniprot.org/uniprot/P62158	FTC	LOOM
http://purl.bioontology.org/ontology/SNMI/F-623D0	SNMI	LOOM
http://www.cea.fr/ontotoxnuc#Calmoduline	ONTOTOXNUC	LOOM
http://purl.obolibrary.org/obo/dinto_0753	DINTO	LOOM
http://purl.bioontology.org/ontology/CSP/2446-4200	CRISP	LOOM
http://purl.obolibrary.org/obo/NCIT_C16375	BERO	LOOM
http://purl.obolibrary.org/obo/OMIT_0003488	OMIT	LOOM
http://purl.jp/bio/4/id/200906016501904937	IOBC	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16375	NCIT	LOOM
http://purl.org/sig/ont/fma/fma62343	FMA	LOOM
http://doe-generated-ontology.com/OntoAD#C0006772	ONTOAD	LOOM
http://www.bioassayontology.org/bao#BAO_0200422	BAO-GPCR	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.157.125.412.249	RH-MESH	LOOM
http://www.projecthalo.com/aura#Calmodulin	AURA	LOOM
http://purl.obolibrary.org/obo/MESH_D002147	BERO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00021845	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/41649004	SNOMEDCT	LOOM