Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D002120 http://purl.bioontology.org/ontology/MESH/D002120
Preferred Name	Calcium Channel Agonists
Definitions	Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in VASCULAR SMOOTH MUSCLE and/or CARDIAC MUSCLE cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture.
Synonyms	Channel Activators, Calcium Agonists, Calcium Channel Calcium Channel Activators Calcium Channel Agonist Activators, Calcium Channel Calcium Channel Agonists, Exogenous Channel Agonist, Calcium Exogenous Calcium Channel Agonists Channel Agonists, Calcium Agonist, Calcium Channel
Type	http://www.w3.org/2002/07/owl#Class

definition	Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in VASCULAR SMOOTH MUSCLE and/or CARDIAC MUSCLE cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture.
altLabel	Channel Activators, Calcium Agonists, Calcium Channel Calcium Channel Activators Calcium Channel Agonist Activators, Calcium Channel Calcium Channel Agonists, Exogenous Channel Agonist, Calcium Exogenous Calcium Channel Agonists Channel Agonists, Calcium Agonist, Calcium Channel See more See less
prefLabel	Calcium Channel Agonists
EC	antagonists & inhibitors:Calcium Channel Blockers
Machine permutation	88
HN	88
type	http://www.w3.org/2002/07/owl#Class
tui	T121
TERMUI	T006036 T006037 T006039 T006040 T006038
TH	NLM (1995) UNK (19XX) NLM (1988)
MMR	20180522
notation	D002120
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D015220
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T121
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
DX	19880101
cui	C0015288 C0006683
DC	1
MN	D27.505.696.260.250 D27.505.519.562.124 D27.505.954.411.793.205
AQL	AD AE AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
Inverse of RB	0
Inverse of isa	http://purl.bioontology.org/ontology/MESH/C102635 http://purl.bioontology.org/ontology/MESH/D002117 http://purl.bioontology.org/ontology/MESH/C040525 http://purl.bioontology.org/ontology/MESH/D001498 http://purl.bioontology.org/ontology/MESH/C490483 http://purl.bioontology.org/ontology/MESH/C045796 http://purl.bioontology.org/ontology/MESH/C117862 http://purl.bioontology.org/ontology/MESH/C085029 http://purl.bioontology.org/ontology/MESH/C071658 http://purl.bioontology.org/ontology/MESH/C049834 See more See less
MDA	19990101
subClassOf	http://purl.bioontology.org/ontology/MESH/D000077264 http://purl.bioontology.org/ontology/MESH/D014662 http://purl.bioontology.org/ontology/MESH/D049990

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display