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Last uploaded:
January 16, 2025
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| Id | http://purl.bioontology.org/ontology/MESH/D002047
http://purl.bioontology.org/ontology/MESH/D002047
|
|---|---|
| Preferred Name | Buprenorphine |
| Definitions |
A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
|
| Synonyms |
6029 M
6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, (5alpha,7alpha(S))-
Buprex
Subutex
Hydrochloride, Buprenorphine
RX 6029 M
6029M
RX-6029-M
Temgesic
Prefin
Buprenorphine Hydrochloride
RX6029M
Temgésic
6029-M
Buprenex
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use. |
|---|---|
| altLabel |
6029 M
6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, (5alpha,7alpha(S))-
Buprex
Subutex
Hydrochloride, Buprenorphine
RX 6029 M
6029M
RX-6029-M
Temgesic
Prefin
Buprenorphine Hydrochloride
RX6029M
Temgésic
6029-M
Buprenex
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|
| prefLabel |
Buprenorphine
|
| TH |
USAN (1976)
US
MX
UK
NL
FDA SRS (2014)
ES
UNK (19XX)
INN (19XX)
DE
AU
USP (19XX)
BAN (19XX)
FR
IE
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|
| notation |
D002047
|
| RR |
52485-79-7 (Buprenorphine)
53152-21-9 (HCl)
56W8MW3EN1
|
| DX |
19870101
|
| Machine permutation |
87; was see under MORPHINANS 1979-86
|
| MN |
D03.633.400.686.150
D03.132.577.249.150
D03.605.497.150
D04.615.723.795.150
|
| PA |
D009292
D000701
D009294
|
| FX |
D058850
|
| MMR |
20170524
|
| Mapped from |
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|
| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
|
| HN |
87(79); was see under MORPHINANS 1979-86
|
| subClassOf | |
| Semantic type UMLS property | |
| Inverse of RB |
40D3SCR4GZ
0
56W8MW3EN1
|
| LT |
TRD
|
| DC |
1
|
| MDA |
19780317
|
| Inverse of RO | |
| type | |
| tui |
T109
T121
|
| cui |
C0701441
C0701445
C1450937
C0006405
C0729137
C0006404
C5441581
C5441582
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|
| isa | |
| AN |
for buprenorphine maintenance treatment, coordinate with OPIATE SUBSTITUTION TREATMENT
|
| Inverse of AQ |
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|
| TERMUI |
T005809
T585649
T585650
T005807
T005812
T585653
T005810
T585643
T005808
T005811
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|
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