Medical Subject Headings

Last uploaded: January 31, 2024

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Preferred Name	Antidepressive Agents, Tricyclic
Synonyms	Antidepressant Drugs, Tricyclic
Definitions	Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
ID	http://purl.bioontology.org/ontology/MESH/D000929
altLabel	Antidepressant Drugs, Tricyclic Tricyclic Antidepressants Antidepressants, Tricyclic Tricyclic Antidepressant Drug, Tricyclic Antidepressant Agents, Tricyclic Antidepressive Antidepressive Agent, Tricyclic Tricyclic Antidepressive Agents Antidepressant, Tricyclic Tricyclic Antidepressive Agent Drugs, Tricyclic Antidepressant Antidepressant Drug, Tricyclic Tricyclic Antidepressant Drugs Tricyclic Antidepressant Drug Agent, Tricyclic Antidepressive
AQL	AD AE AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0003290
DC	1
definition	Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
DX	19750901
HN	75
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of isa	http://purl.bioontology.org/ontology/MESH/D007488 http://purl.bioontology.org/ontology/MESH/D008127 http://purl.bioontology.org/ontology/MESH/D009888 http://purl.bioontology.org/ontology/MESH/D007099 http://purl.bioontology.org/ontology/MESH/C005100 http://purl.bioontology.org/ontology/MESH/D000639 http://purl.bioontology.org/ontology/MESH/C084605 http://purl.bioontology.org/ontology/MESH/D002997 http://purl.bioontology.org/ontology/MESH/C011597 http://purl.bioontology.org/ontology/MESH/C028701 http://purl.bioontology.org/ontology/MESH/C004704 http://purl.bioontology.org/ontology/MESH/D004316 http://purl.bioontology.org/ontology/MESH/C001834 http://purl.bioontology.org/ontology/MESH/D004308 http://purl.bioontology.org/ontology/MESH/D014299 http://purl.bioontology.org/ontology/MESH/C050504 http://purl.bioontology.org/ontology/MESH/C028653 http://purl.bioontology.org/ontology/MESH/D000657 http://purl.bioontology.org/ontology/MESH/D003891 http://purl.bioontology.org/ontology/MESH/C012677 http://purl.bioontology.org/ontology/MESH/C100240 http://purl.bioontology.org/ontology/MESH/D009661 http://purl.bioontology.org/ontology/MESH/D011530
Inverse of RB	0
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D018759
Machine permutation	75
MDA	19741111
MMR	20210630
MN	D27.505.954.427.700.122.055
notation	D000929
prefLabel	Antidepressive Agents, Tricyclic
TERMUI	T001008778 T002765 T001008779 T002764 T002763 T002766 T001008777
TH	NLM (1995) NLM (1975) UNK (19XX) NLM (2021)
tui	T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D000928

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/SNOMEDCT/373253007	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/LNC/LA28423-4	LOINC	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/33219003	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SCTSPA/33219003	SCTSPA	CUI
http://purl.bioontology.org/ontology/SCTSPA/373253007	SCTSPA	CUI
http://purl.bioontology.org/ontology/LNC/LP14735-2	LOINC	CUI
http://purl.bioontology.org/ontology/VANDF/4021595	VANDF	CUI
http://purl.bioontology.org/ontology/MSHFRE/D000929	MSHFRE	CUI
http://purl.bioontology.org/ontology/RCD/d7...	RCD	CUI
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0003290	MEDLINEPLUS	CUI
http://purl.bioontology.org/ontology/SNMI/C-62200	SNMI	CUI
http://purl.bioontology.org/ontology/CSP/4000-0355	CRISP	CUI
http://purl.bioontology.org/ontology/LNC/MTHU001920	LOINC	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000029148	NDFRT	CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D000929	RH-MESH	LOOM
http://purl.obolibrary.org/obo/OMIT_0002326	OMIT	LOOM
http://id.nlm.nih.gov/mesh/D000929	MDM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D27.505.954.427.700.122.055	RH-MESH	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00024957	PMAPP-PMO	LOOM
http://purl.obolibrary.org/obo/MESH_D000929	BERO	LOOM