Medical Subject Headings

Last uploaded: August 28, 2024
Preferred Name

Alkylating Agents
Synonyms

Agent, Alkylating

Alkylators

Alkylating Agent

Agents, Alkylating

Alkylator

Definitions

Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.

ID

http://purl.bioontology.org/ontology/MESH/D000477

altLabel

Agent, Alkylating

Alkylators

Alkylating Agent

Agents, Alkylating

Alkylator

AQL

AD AE AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR

cui

C0002073

DC

1

definition

Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.

DX

19660101

HN

66(64)

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000528

Inverse of isa

http://purl.bioontology.org/ontology/MESH/C047543

http://purl.bioontology.org/ontology/MESH/C002531

http://purl.bioontology.org/ontology/MESH/C047693

http://purl.bioontology.org/ontology/MESH/C010243

http://purl.bioontology.org/ontology/MESH/C011612

http://purl.bioontology.org/ontology/MESH/C000470

http://purl.bioontology.org/ontology/MESH/C024524

http://purl.bioontology.org/ontology/MESH/D004052

http://purl.bioontology.org/ontology/MESH/D019813

http://purl.bioontology.org/ontology/MESH/D000590

http://purl.bioontology.org/ontology/MESH/D008770

http://purl.bioontology.org/ontology/MESH/D014011

http://purl.bioontology.org/ontology/MESH/D016685

http://purl.bioontology.org/ontology/MESH/D009605

http://purl.bioontology.org/ontology/MESH/C052475

http://purl.bioontology.org/ontology/MESH/C051731

http://purl.bioontology.org/ontology/MESH/D007461

http://purl.bioontology.org/ontology/MESH/D007460

http://purl.bioontology.org/ontology/MESH/D000099

http://purl.bioontology.org/ontology/MESH/D005038

http://purl.bioontology.org/ontology/MESH/C014114

http://purl.bioontology.org/ontology/MESH/C088674

http://purl.bioontology.org/ontology/MESH/D014108

http://purl.bioontology.org/ontology/MESH/D014107

http://purl.bioontology.org/ontology/MESH/D002066

http://purl.bioontology.org/ontology/MESH/D008466

http://purl.bioontology.org/ontology/MESH/C007482

http://purl.bioontology.org/ontology/MESH/C030667

Inverse of RB

0

Inverse of RO

http://purl.bioontology.org/ontology/MESH/D009153

Machine permutation

66

MDA

19990101

MMR

20200527

MN

D27.888.569.035

D27.505.519.124

notation

D000477

prefLabel

Alkylating Agents

TERMUI

T001078757

T001417

T001416

T001078758

TH

NLM (1996)

NLM (2021)

NLM (1964)

tui

T131

T121

subClassOf

http://purl.bioontology.org/ontology/MESH/D009676

http://purl.bioontology.org/ontology/MESH/D045504

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