Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D000099120
http://purl.bioontology.org/ontology/MESH/D000099120
Preferred Name

Bioisosterism

Definitions
A strategy used in PHARMACEUTIC CHEMISTRY where one part of a molecule is replaced with a different one that has similar physical or chemical properties, but with the aim of enhancing the biological activity, stability, or safety of the molecule.
Synonyms
Modification, Bioisosteric
Substitution, Bioisosteric
Design, Bioisosteric
Bioisosteric Design
Bioisosteric Substitutions
Bioisosteric Modification
Bioisosteric Substitution
Bioisosteric Replacement
Bioisosteric Modifications
Bioisosteric Replacements
Replacement, Bioisosteric
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Type http://www.w3.org/2002/07/owl#Class
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