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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D000096785
http://purl.bioontology.org/ontology/MESH/D000096785
|
|---|---|
| Preferred Name | Neuroligins |
| Definitions |
Postsynaptic cell-adhesion molecules that bind presynaptic NEUREXINS to form calcium-dependent trans-synaptic adhesions. Neuroligins recruit synaptic scaffolding proteins (e.g., PSD-95) via their PDZ DOMAIN. The distribution and interaction with neurexins are regulated by ALTERNATIVE SPLICING. Alterations in genes encoding neuroligins or neurexins are associated with cognitive diseases such as AUTISM SPECTRUM DISORDER.
|
| Synonyms |
Neuroligin
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Postsynaptic cell-adhesion molecules that bind presynaptic NEUREXINS to form calcium-dependent trans-synaptic adhesions. Neuroligins recruit synaptic scaffolding proteins (e.g., PSD-95) via their PDZ DOMAIN. The distribution and interaction with neurexins are regulated by ALTERNATIVE SPLICING. Alterations in genes encoding neuroligins or neurexins are associated with cognitive diseases such as AUTISM SPECTRUM DISORDER. |
|---|---|
| altLabel | Neuroligin
|
| prefLabel | Neuroligins
|
| Machine permutation | 2024
|
| HN | 2024
|
| type | |
| tui |
T116
T123
|
| TERMUI |
T001136282
T001132664
|
| TH | NLM (2024)
|
| MMR | 20240101
|
| notation | D000096785
|
| Semantic type UMLS property | |
| Inverse of AQ |
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|
| DX | 20240101
|
| cui | C1325366
|
| DC | 1
|
| MN |
D12.776.631.641
D12.776.543.550.200.250.520.894
D09.400.430.890.200.250.520.894
D23.050.301.350.250.520.894
D12.776.395.550.200.250.520.894
|
| AQL | AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
|
| Inverse of RB | 0
|
| MDA | 20230207
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |